Abstract: According to the characteristics of chloride saline-alkali soil in Hotao area,the effects of 201×4 strongly basic styrene anion exchange resin mix with three kinds of acidic materials （humic acid, peat, mono-ammonium phosphate） on the passivation effect of salt and alkali was studied through indoor soil improvement experiment in this paper. The results show that application effect is outstanding when the 201×4 resin application rate is 2%, and mix with peat in 1 ： 1.5 ratio. Compared with the CK, the content of water-soluble Na^＋ in soil decreased by 21.41%, the content of water-soluble Cl- decreased by 34.36%, the content of water-soluble SO4^2- decreased by 87.88% and the content of total soluble salt in soil decreased by 30.64%. The soil pH decreased by 0.78 compared with the single application of 201×4 resin. They could be used as the materials to improve saline-alkali soil in the future.