Abstract: With the rise of people′s living standards, the demand for milk has significantly increased. But all kinds of cattle diseases have become important factors that restrict the development of dairy cow. The ketosis of dairy cow is a kind of nutritional metabolic disease that commonly occurs in high-yield cow, which would cause obvious decrease of milk yield and conception rate. The etiology, occurrence rule and clinical symptoms of the ketosis of dairy cow were mainly introduced and some concrete control measures were proposed, so as to provide references for the majority of farmers.