畜牧与饲料科学 ›› 2014, Vol. 35 ›› Issue (1): 5-5.doi: 10.12160/j.issn.1672-5190.2014.01.004

• 基础科学 • 上一篇    下一篇

半胱胺对藏绵羊断奶羔羊血清GH、SS、IGF-1水平的影响

宋天增[1] 冯静[1] 夏晨阳[1] 鲍宇红[2] 冯柯[3] 石国庆[4]   

  1. [1]西藏自治区农牧科学院畜牧兽医研究所,西藏拉萨850009 [2]西藏自治区农牧科学院草业科学研究所,西藏拉萨850000 [3]西藏拉萨市动物疫病预防控制中心,西藏拉萨850009 [4]新疆农垦科学院兵团绵羊繁育生物技术重点实验室,新疆石河子832000
  • 出版日期:2014-01-20 发布日期:2014-01-20
  • 通讯作者: 宋天增
  • 作者简介:宋天增(1980-),男,助理研究员,硕士,主要研究方向为高原畜禽营养与繁殖。 通讯作者:石国庆(1959-),男,研究员,博士生导师,主要研究方向为绵羊繁育。
  • 基金资助:
    863计划项目(2011AA100307);科技支撑计划(2011BAD28805-1-1);国家自然科学基金(31360540);西藏自治区自然科学基金.

Effects of Cysteamine on the Levels of GH, SS and IGF-1 in the Serum of Tibetan Sheep Weaned Lamb

SONG Tian-zeng, FENG Jing, XIA Chen-yang, BAO Yu-hong, FENG Ke, SHI Guo-qing (1.Institute of Animal Husbandry and Veterinary Medicine,Tibet Academy of Agricultural and Animal Husbandry Sciences, Lhasa 850009, China; 2.Institute of Grassland Science,Tibet Academy of Agricultural and Animal Husbandry Sciences, Lhasa 850000, China; 3.Lhasa Center for Prevention and Control of Animal Diseases, Lhasa 850009, China; 4.Key Laboratory of Sheep Breeding & Biotechnology in Xinjiang Production and Construction Group, Xinjiang Academy of Agricultural and Reclamation Sciences,Shihezi 832000,China)   

  • Online:2014-01-20 Published:2014-01-20

摘要: 试验研究了半胱胺(CS)对藏绵羊断奶羔羊血清中生长激素(GH)、生长抑素(SS)、血清中胰岛素样生长因子(IGF-1)的影响。将40只80日龄左右且始重平均为16 kg的(公母各半)藏绵羊断奶羔羊随机分为2组,在日粮精料中添加300 mg/(kg·BW)的CS,隔日添加1次,试验期42 d。分别于开始用药后的第0、7、14、21、28、35天早晨空腹颈静脉采血样,以放射免疫法测定血浆中GH、SS、IGF-1。结果表明,试验组精料中添加CS使藏绵羊断奶羔羊血清GH、IGF-1都有不同程度的提高,且试验组与对照组相比都有显著差异(P〈0.05);SS均有不同程度的下降,试验组与对照组相比第3周开始有显著差异(P〈0.05)。

Abstract: The effects of cysteamine on GH, SS and IGF-1 in the serum of Tibetan Sheep weaned lamb were studied. 40 80-day-old weaned lambs of Tibetan Sheep with the average initial weight of 16 kg(half male and half female) were randomly divided into 2 groups. 300 mg/(kg·BW) of CS was added in the concentrate of diet every two days. The trial lasted 42 days. The blood samples were collected from empty stomach of sheep by jugular vein in the morning of the 0th, 7th, 14th, 21st, 28th and 35th day after medication. The content of GH, SS and IGF-1 in the plasma was determined by radioimmunoassay. The results showed that adding CS in the concentrate in the test group could increase the content of GH and IGF-1 in the serum of weaned lambs of Tibetan Sheep to different extent and there was significant difference between test group and control group(P〈0.05). SS decreased to different extent and SS content in test group had significant difference with that in control group from the 3rd week to the 42nd day.

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