Abstract: This paper taking ecology,geography,sociology,economic theory as a guide,systematicly analyze the main problems of Chang-Zhu-Tan urban agglomeration ecological spatial structure and their impact factors and shows the structural optimization of the ecological space of the goals and ambitions.The research results show that： Eco-matrix has not yet formed;green patches lack connections between them during natural ecological processes,the important natural space corridor is somewhat blocked,and also,with the capacity of resources and environment gradually weakened.The form of these problems are the comprehensive consequences of Chang-Zhu-Tan urban agglomeration poor ecological spatial structure of the main problems that the natural factors of the formation of closed and the combined effects of socio-economic factors.Government should through various means to improved regional infrastructure enhance the advantage of Chang-Zhu-tan,and through regional policy,urban planning,such as macro-control means guide the Chang-Zhu-tan to achieve the optimal spatial structure of ecological restructure and promote the overall group of cities sustainable development.