Abstract: A rapid detection of eight kinds of pesticide residues in red bean,mung bean and sorghum rice was established.The samples were extracted by acetonitrile and detected by ultra high performance liquid chromatography tandem mass spectrometry.Two steps of purification and concentration were simplified.Results show that standard addition recovery rate of eight kinds of pesticide residues was 80.20%-125.55% and relative standard deviation was 0.2%-7.0%.The standard addition recovery rates of seven pesticide residues were in the allowed range besides one is slightly higher than 120%.The method could be used in the determination of many kinds of pesticide residues in grain.