Brachyury基因的研究进展

doi:10.12160/j.issn.1672-5190.2019.04.016

畜牧与饲料科学 ›› 2019, Vol. 40 ›› Issue (4): 58-61.doi: 10.12160/j.issn.1672-5190.2019.04.016

Brachyury基因的研究进展

龙鑫[1,2];智达夫[3];何亭漪[3];李晓丹[3];杨红新[3];曹贵方[3]

[1]内蒙古农业大学生命科学学院,内蒙古呼和浩特010018;[2]内蒙古自治区基础兽医学重点实验室,内蒙古呼和浩特010018;[3]内蒙古农业大学兽医学院,内蒙古呼和浩特010018

收稿日期:2019-03-30 出版日期:2019-04-30 发布日期:2019-08-19
通讯作者: 龙鑫-内蒙古农业大学生命科学学院,内蒙古呼和浩特010018
作者简介:龙鑫(1993—),男,硕士研究生,主要研究方向为细胞生物学;通讯作者:曹贵方(1963-),男,教授,博士,博士生导师,主要研究方向为动物组织胚胎与发育生物学。
基金资助:
国家自然科学基金项目(3186130045)。

Research Progress of Brachyury Gene

LONG Xin[1,2];ZHI Da-fu[3];HE Ting-yi[3];LI Xiao-dan[3];YANG Hong-xin[3];CAO Gui-fang[3]

[1]College of Life Sciences,Inner Mongolia Agricultural University,Hohhot 010018,China;[2]Inner Mongolia Key Laboratory of Basic Veterinary Medicine,Hohhot 010018,China;[3]College of Veterinary Medicine,Inner Mongolia Agricultural University,Hohhot 010018,China

Received:2019-03-30 Online:2019-04-30 Published:2019-08-19

摘要/Abstract

摘要： Brachyury基因是T-box基因家族编码的一种转录因子,该基因已经在包括腔肠动物在内的许多动物中发现。Brachyury基因在调控生物体胚胎发育、细胞迁移等许多方面扮演着重要角色,其功能还涉及胚胎发育过程中器官形成等生理过程。研究发现,人类肿瘤疾病、动物脊索发育、动物尾型的畸形生长都与Brachyury基因有直接联系。主要就Brachyury基因与肿瘤疾病、动物短尾性状形成的研究进展进行综述,以期为相关研究提供参考。

关键词: Brachyury基因;肿瘤;短尾性状;研究进展

Abstract: The Brachyury gene is a transcription factor encoded by the T-box gene family,which has been found in many animals including coelenterates.It plays an important role in regulating embryonic development,cell migration and other aspects of the organism.Its function also involves certain physiological processes such as organ formation during embryonic development.It has been found that Brachyury gene is directly associated with human tumor diseases,the development of chordal cord and the abnormal growth of tail type in animals.In this paper,the research progress of involvement of Brachyury gene in tumor disease and formation of short tail traits in animals was reviewed.

中图分类号:

龙鑫,智达夫,何亭漪,李晓丹,杨红新,曹贵方. Brachyury基因的研究进展[J]. 畜牧与饲料科学, 2019, 40(4): 58-61.

LONG Xin,ZHI Da-fu,HE Ting-yi,LI Xiao-dan,YANG Hong-xin,CAO Gui-fang(College of Life Sciences,Inner Mongolia Agricultural University,Hohhot 010018,China,Inner Mongolia Key Laboratory of Basic Veterinary Medicine,Hohhot 010018,China,College of Veterinary Medicine,Inner Mongolia Agricultural University,Hohhot 010018,China). Research Progress of Brachyury Gene[J]. Animal Husbandry and Feed Science, 2019, 40(4): 58-61.

Brachyury基因的研究进展

Research Progress of Brachyury Gene

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