畜牧与饲料科学 ›› 2019, Vol. 40 ›› Issue (3): 99-104.doi: 10.12160/j.issn.1672-5190.2019.03.025

• 著者文摘 • 上一篇    下一篇

犬污染骨异位寄养再回植的影像学评估

仇爽[1];王峥[1];聂静[1];朱婷婷[1];韦人月[1];阮红日[1];魏雪[1];郑家三[1]   

  1. [1]黑龙江八一农垦大学动物科技学院,黑龙江大庆163319
  • 收稿日期:2019-01-15 出版日期:2019-03-30 发布日期:2019-08-19
  • 通讯作者: 仇爽-黑龙江八一农垦大学动物科技学院,黑龙江大庆163319
  • 作者简介:仇爽(1993—),女,硕士研究生,主要研究方向为小动物疾病学;通讯作者:郑家三(1978-),男,副教授,博士,主要研究方向为奶牛肢蹄病、小动物外科学。
  • 基金资助:
    国家重点研发计划项目(2016YFD0501008)。

Imaging Evaluation of Canine Contaminated Bone Ectopic Fostering and Replantation

QIU Shuang[1];WANG Zheng[1];NIE Jing[1];ZHU Ting-ting[1];WEI Ren-yue[1];RUAN Hong-ri[1];WEI Xue[1];ZHENG Jia-san[1]   

  1. [1]College of Animal Science and Veterinary Medicine,Heilongjiang Bayi Agricultural University,Daqing 163319,China
  • Received:2019-01-15 Online:2019-03-30 Published:2019-08-19

摘要: [目的]探讨犬游离长段桡骨通过寄养在血运丰富的隐静脉旁使其血管化来修复开放性骨折造成的骨缺损的可行性。[方法]选取12只成年健康犬随机分为实验组与对照组,2组分别截取右侧前肢桡骨中段约15mm的桡骨骨段。模拟车祸环境,将截取的长段桡骨放置于外界泥土中1h,取回的骨块用大量生理盐水冲洗,并放置在10%聚维酮碘中浸泡5min,之后使用生理盐水冲洗1min,沥干备用。实验组将其包埋在血管丰富的隐静脉处,对照组放置于-80℃低温无菌保存。8周后取出骨块,植回原位修复犬桡骨骨缺损。回植后第6、12周观察桡骨的大体形态。第4、8、12周通过X射线观察修复效果,使用Lane-SandhuX线评分标准进行评分。[结果]在同一时间段内,实验组桡骨骨缺损修复的效果均好于对照组。[结论]通过寄养血管化的长段骨和低温保存长段骨均可修复犬桡骨骨缺损,与-80℃保存的骨块相比血管化的长段骨具有愈合时间短、骨吸收少的优点。

关键词: 犬;骨寄养;骨缺损;血管化;影像学

Abstract: [Objective]To investigate the feasibility of repairing bone defects associated with open fractures by vascularization of canine free long segmental radius via fostering in the blood-rich saphenous vein.[Method] A total of 12 healthy dogs were randomly divided into experimental group and control group.For both of the groups,a bone segment with length of 15 mm in middle part of radius of right forelimb was amputated.Under the simulated traffic accident condition,the amputated long radial segment was kept in soil outside for 1 h.Subsequently,the retrieved bone segment was subjected to a series of treatments,including washing with plenty of physiological saline,immersing in 10% povidone-iodine for 5 min,flushing using physiological saline for 1 min,and draining off for further use.For experimental group,the radial segment was embedded in the blood-rich saphenous vein,and for control group,it was preserved at -80 ℃ in a sterile condition.After 8 weeks,the bones were removed and implanted back to repair the canine radial defect.Gross morphology of the bones was observed at 6 and 12 weeks after replantation.The repair effect was evaluated by X-ray at weeks of 4,8,and 12,respectively,and was scored using the Lane-Sandhu X-ray scoring standard.[Result] In the same period of time,the better repair effect of radial defect was observed in the experimental group compared to the control group.[Conclusion] The canine radial defect can be repaired by fostering the vascularized long bone segment or cryopreserving the long bone segment.Compared with the bone segment preserved at -80 ℃,the vascularized one has the advantages of shorter healing time and less bone resorption.

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