畜牧与饲料科学 ›› 2010, Vol. 31 ›› Issue (3): 62-62.doi: 10.12160/j.issn.1672-5190.2010.03.025

• 中草药科学 • 上一篇    下一篇

中药复方透皮贴剂药效作用的研究

冯士彬 周凡 孟庆娟 王希春 韩春杨 吴金节   

  1. 安徽农业大学动物科技学院,安徽合肥230036
  • 出版日期:2010-03-20 发布日期:2010-03-20
  • 通讯作者: 冯士彬
  • 作者简介:冯士彬(1984-),男,硕士,主要研究方向为兽医临床诊疗技术及兽医中药制剂。 通讯作者:吴金节(1962-),男,教授,主要研究方向为畜禽营养代谢病及兽医临床诊疗技术。
  • 基金资助:
    安徽省科技攻关项目(08010302157)

Drug Action of Compound Traditional Chinese Medicine Transdermal Patch

FENG Shi-bin,ZHOU Fan,MENG Qing-juan,WANG Xi-chun,HAN Chun-yang,WU Jin-jie (College of Animal Science and Technology,Anhui Agricultural University,Hefei 230036,China)   

  • Online:2010-03-20 Published:2010-03-20

摘要: 该试验旨在研究中药复方透皮贴剂的药效作用。结果显示,中药复方透皮贴剂提取液对金黄色葡萄球菌、表皮葡萄球菌、大肠杆菌具有很好的抑菌效果,可显著抑制二甲苯所致小鼠耳廓的肿胀度(P〈0.01或P〈0.05),对乙酸致小鼠腹腔毛细血管通透性也有明显的抑制作用(P〈0.01或P〈0.05),能减少乙酸所致小鼠的扭体次数。结果证实,中药复方透皮贴剂具有较好的抑菌、抗炎、镇痛作用。

Abstract: The aim of this research was to explore the drug action of the compound traditional Chinese medicine transdermal patch.The results showed that the extracting solution of compound traditional Chinese medicine transdermal patch had good bacteriostasis on Staphylococcus aureus,Staphylococcus epidermidis and Escherichia coli.It also had significant resistant effects on dimethylbenzene inducing ear edema model (P〈0.01 or 0.05).It had a significant inhibitory action on acetic acid inducing mouse abdominal capillary permeability (P〈0.01 or 0.05) and resisted the writhing action caused by acetic acid.The experiment indicated that the compound traditional Chinese medicine transdermal patch had good bacteriostasis,anti-inflammatory and analgesia effect.

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