Abstract: With the rapid development of livestock industry in China,a large amount of manure produced by livestock has become the most serious pollution source.The contamination of livestock manure may result in ecological environment destruction in the future if not be treated in time.The innocuous microorganism inoculants play an important role in the re-utilization of livestock manure.They can fully decompose the organic matter and release nutrients through microbe fermentation.Furthermore,the high temperature generated during the fermentation can kill pathogenic microorganisms and parasite eggs as well as produce high-quality microbial organic fertilizer,which is favorable to the purification of the environment.In this paper,the application of microorganism inoculants in livestock manure treatment and the effect of microbial organic fertilizer were briefly introduced.