不同驱虫药对伊犁马驱虫效果及血液生理指标的影响

doi:10.12160/j.issn.1672-5190.2023.02.018

Abstract

Abstract:

[Objective] The present study aimed to investigate the changes in the species and quantity of parasitic eggs in feces of Yili horses before and after administration of different anthelmintic drugs, and to assess the effects of anthelmintic drugs on blood physiological parameters of the horses. [Method] A total of 40 one-year-old Yili horses with an average weight of （265.5 ± 35.6） kg and similar birth dates were selected and randomly divided into 5 groups, including the control group （n=8）, experiment groupⅠ（n=8）, experiment groupⅡ （n=8）, experiment group Ⅲ （n=8） and experiment group Ⅳ （n=8）. Under the same feeding and management condition as well as dietary nutritional level, ivermectin was given to experiment groupⅠ, praziquantel was given to experiment groupⅡ, albendazole was given to experiment group Ⅲ, a combination of ivermectin and albendazole was given to experiment group Ⅳ, and no anthelmintic drugs were given to the control group. The fecal samples of the horses were collected before deworming and on days 1, 2, 3, 7 and 14 after deworming. Parasitic eggs were then identified and counted to calculate the parasite infection rate. On day 14 after deworming, the blood samples of the horses were collected and blood physiological parameters were measured. [Result]① On day 14 after deworming, except for the large number and varieties of parasitic eggs in the control group and a tiny number of parasitic eggs in experiment group Ⅱ, no parasitic eggs were found in the other experiment groups. The eggs per gram （EPG） in experiment groupsⅠ, Ⅲ and Ⅳ all decreased by 612.50 （P<0.01） compared to the control group, and the EPG in experiment group Ⅱ decreased by 562.50 （P<0.01）. ②The number of monocytes in experiment groupⅠ was extremely significantly （P<0.01） lower than that in the control group. The number of basophilic granulocytes in experiment group Ⅳ was extremely significantly （P<0.01） higher than that in the control group and experiment group Ⅰ, and was significantly （P<0.05） higher than that in experiment groups Ⅱ and Ⅲ. The percentage of basophilic granulocytes in experiment group Ⅳ was extremely significantly （P<0.01） higher than that in the control group, and was significantly （P<0.05） higher than that in experiment groups Ⅰ and Ⅱ. The mean corpuscular hemoglobin concentration in experiment group Ⅳ was extremely significantly （P<0.01） higher than that in experiment groups Ⅰ and Ⅱ. ③The mean platelet volume in both the control group and experiment group Ⅰ was significantly （P<0.05） higher than that in experiment group Ⅳ. [Conclusion] The 4 anthelmintic drugs or their combinations have prominent anthelmintic effects on intestinal parasites in Yili horses. Among them, albendazole significantly reduces the EPG in horse feces, effectively prevents and treats parasitic infections, and has positive impact on horse blood physiological parameters.

Key words: anthelmintic drugs, Yili horse, anthelmintic effect, blood physiology

CLC Number:

S858.219.795

MA Yuhui, CHEN Haonan, JIANG Shuo, Ayinigaer Abulaiti, LI Hai, Yeshatti Juan, Nulan Akyazi, YANG Kailun. Efficacy of Different Anthelmintic Drugs and Their Effects on Blood Physiological Parameters in Yili Horses[J]. Animal Husbandry and Feed Science, 2023, 44(2): 121-128.

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References 29

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Efficacy of Different Anthelmintic Drugs and Their Effects on Blood Physiological Parameters in Yili Horses

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