Abstract: In recent years, with the rapid development of the modern grassland husbandry and the increasing attention on ecological environment protection in Anshun region of Guizhou Province, the comprehensive utilization has been constantly improved in this region. In this paper, we introduced the comprehensive utilization status of crop straw in Anshun region of Guizhou Province, analyzed the important roles of improving comprehensive utilization of crop straw plays in the local development of animal husbandry and improvement of ecological environment, and proposed some countermeasures in view of the existing problems and difficulties in comprehensive utilization of crop straw in this region.