Abstract: Catalytic antibody（also known as abzyme） is a kind of immunoglobulin with catalytic.Because it has high selectivity and amazing diversity as antibodies and highly catalytic as enzymes,it is anticipated that using abzyme preparation technology one can obtain any kind of tailor-made biocatalysts,including those not occurred in nature,for various kinds of practical application.Thus,abzyme study has an important value in theory and practice for biology,chemistry and research are summarized with a special emphasis on the breadth and scope of new antibody-catalyzed reactions and novel hapten design strategies.The advances of catalytic antibodies research are summarized with abzymes structure,of nature and their preparings,a method to produce and the filtering method,enzymology character and the latest progresses in catalytic antibodies.