北方农业学报 ›› 2014, Vol. ›› Issue (2): 119-119.

• 专题■■■述评 • 上一篇    下一篇

DNAzyme在疾病治疗中的应用研究进展

刘燕   

  1. 内蒙古民族大学生命科学学院,内蒙古通辽028043
  • 出版日期:2014-04-20 发布日期:2014-04-20
  • 通讯作者: 刘燕
  • 作者简介:刘燕(1979-),女,内蒙古化德人,讲师,硕士,研究方向:分子细菌学。
  • 基金资助:
    内蒙古自治区高等学校科学技术研究项目(NJZY12119);内蒙古自然科学基金项目(2013MS0403)

Applications of DNAzymes in the Disease Treatment

LIU Yan (College of Life Science,Inner Mongolia University for Nationalities,Tongliao 028043,China)   

  • Online:2014-04-20 Published:2014-04-20

摘要: 脱氧核酶(DNAzyme)是一类具有多种催化功能的单链DNA分子,在多种疾病的基因治疗中显示出巨大潜力,尤其对肿瘤、病原微生物的作用有着广阔的应用前景和一定的临床实用价值.文章就DNAzyme的作用机理及其在抗疾病方面的研究现状等方面做一综述.

Abstract: Deoxyribozmes (DNAzymes) are a set of single stranded DNA segments with a variety of catalytic functions. It shows great potential in gene therapy of many diseases, especially has broad application prospects and clinical practical value for the tumor and the pathogenic microorganisms. In this paper,the mechanism of action of DNAzyme and its applications in the disease treatment were reviewed.

中图分类号: 

  • Q55