Abstract: The industrialized research results of the optimization of the technical parameters of synergistic solid state fermentation of producing soybean oligopeptide protein feed with the two kinds of bacteria were summarized. The model was as follows： combination of two kinds of bacteria → liquid state inoculation→ closed fermentation in fermentation pool. The two kinds of bacteria were screened out： Bacillus subtilis and Lactobacillus. The optimized fermentation technical parameters were as follows： the fermentation time of 38 h, pH of 7～8, the initial temperature of （37±1） ℃, the inoculated volume of 2% Bacillus subtilis and 3% Lactobacillus, the feed-water ratio of 2∶1, the substrate composition of 90% soybean meal, 7% wheat bran and 3% maize meal.