畜牧与饲料科学 ›› 2021, Vol. 42 ›› Issue (3): 39-42.doi: 10.12160/j.issn.1672-5190.2021.03.007

• 动物营养与饲料科学 • 上一篇    下一篇

替代抗生素饲料添加剂研究进展

由大鹏1, 张絮颖1, 刘丽娜2, 红敏3, 吴国庆4, 高凤林5   

  1. 1.通辽市农牧科学研究所,内蒙古 通辽 028007;
    2.包头轻工职业技术学院,内蒙古 包头 014000;
    3.赤峰市农牧业科学研究院,内蒙古 赤峰 024000;
    4.扎鲁特旗动物卫生监督所,内蒙古 扎鲁特旗 029100;
    5.奈曼旗动物疫病预防与控制中心,内蒙古 奈曼旗 028300
  • 收稿日期:2021-02-07 出版日期:2021-05-30 发布日期:2021-06-21
  • 作者简介:由大鹏(1982—),男,助理研究员,硕士,主要从事动物营养与饲养管理技术研究工作。

Research Advances on Substitutes for Antibiotics Additives

YOU Da-peng1, ZHANG Xu-ying1, LIU Li-na2, Hongmin3, WU Guo-qing4, GAO Feng-lin5   

  1. 1. Tongliao Institute of Agricultural and Animal Husbandry Sciences,Tongliao 028007,China;
    2. Baotou Light Industry Vocational and Technical College,Baotou 014000,China;
    3. Chifeng Academy of Agricultural and Animal Husbandry Sciences,Chifeng 024000,China;
    4. Animal Health Supervision Institute of Jarud Banner,Jarud Banner 029100,China;
    5. Animal Disease Prevention and Control Center of Naiman Banner,Naiman Banner 028300,China
  • Received:2021-02-07 Online:2021-05-30 Published:2021-06-21

摘要: 抗生素作为主要的饲料添加剂在几十年的广泛应用过程中造成了致病菌耐药性增强、动物免疫力降低、影响动物疫苗的效价、通过食物链影响人体健康等亟待解决的问题。我国农业农村部已发布公告,自2020年起我国饲料全面禁止添加使用抗生素类添加剂,饲料行业正式进入“无抗时代”。长期以来,研究人员积极寻求研发各种抗生素替代品及绿色无害的饲料添加剂,以消除或减轻禁用抗生素带来的一系列影响。就目前主要抗生素替代品的抗菌特点及抗菌机理进行综述,旨在为“禁抗”后抗菌性添加剂在饲料中的应用提供参考。

关键词: 抗生素替代品, 饲料添加剂, 作用机制

Abstract: Antibiotics are used as the main feed additives in livestock and poultry. However, their extensive applications over the past decades have resulted in a series of problems which are needed urgently to be solved. For example, antimicrobial resistance of pathogenic bacteria has been enhanced, animal immunity and animal vaccine titer have been reduced, and human health has been affected through food chain. China′ s Ministry of Agriculture and Rural Affairs had issued a notice that the use of antibiotics additives should be banned in China′ s feed industry since the year of 2020, and the feed industry has officially entered an antibiotic-free era. For a long time, researchers have been actively seeking to develop various antibiotics substitutes as well as green and harmless feed additives to eliminate or mitigate the influences brought by prohibition of using antibiotics. In this paper, the antibacterial characteristics and mechanisms of the main antibiotics substitutes are reviewed, in hoping to provide references for the application of antibacterial additives in feed after the ban of antibiotics.

Key words: antibiotics substitutes, feed additives, action mechanism

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