基于典型相关分析探究阿拉善双峰驼血清激素水平与泌乳性能的相关性

doi:10.12160/j.issn.1672-5190.2023.06.011

畜牧与饲料科学 ›› 2023, Vol. 44 ›› Issue (6): 88-93.doi: 10.12160/j.issn.1672-5190.2023.06.011

基于典型相关分析探究阿拉善双峰驼血清激素水平与泌乳性能的相关性

道勒玛¹, 郭丽丽^2,3, 杜海波⁴, 张文广^2,3,5, 曾亚英⁶

1.阿拉善盟畜牧研究所,内蒙古阿拉善左旗 750306;
2.内蒙古农业大学生命科学学院,内蒙古呼和浩特 010018;
3.内蒙古自治区农业基因组大数据工程研究中心,内蒙古呼和浩特 010018;
4.内蒙古阿拉善盟阿拉善孪井滩生态移民示范区综合执法局,内蒙古阿拉善左旗 750306;
5.内蒙古农业大学动物科学学院,内蒙古呼和浩特 010018;
6.阿拉善盟农畜产品质量安全中心,内蒙古阿拉善左旗 750306

收稿日期:2023-09-13 出版日期:2023-11-30 发布日期:2024-01-11
作者简介:道勒玛（1977—）,女,高级兽医师,主要从事双峰驼育种及应用技术研究工作。
基金资助:
内蒙古自治区科技计划项目“双峰驼产乳性状的分子遗传标记及应用研究”（2019GG363）

Investigation of Correlations between Serum Hormone Levels and Lactation Performance in Alagxa Bactrian Camels Based on Canonical Correlation Analysis

Daolema¹, GUO Lili^2,3, DU Haibo⁴, ZHANG Wenguang^2,3,5, ZENG Yaying⁶

1. Alagxa League Animal Husbandry Research Institute,Alagxa Left Banner 750306,China;
2. College of Life Science,Inner Mongolia Agricultural University,Hohhot 010018,China;
3. Inner Mongolia Engineering Research Center of Genomic Big Data for Agriculture,Hohhot 010018,China;
4. Comprehensive Administrative Law Enforcement Bureau of Alagxa Luanjingtan Ecological Migration Demonstration Zone of Alagxa League of Inner Mongolia,Alagxa Left Banner 750306,China;
5. College of Animal Science,Inner Mongolia Agricultural University,Hohhot 010018,China;
6. Alagxa League Agricultural and Livestock Product Quality and Safety Center,Alagxa Left Banner 750306,China

Received:2023-09-13 Online:2023-11-30 Published:2024-01-11

摘要/Abstract

摘要： [目的]探讨阿拉善双峰驼血清激素水平与泌乳性能的相关性。[方法]选取65峰体况及胎次相近的泌乳初期阿拉善双峰驼,测定其血清激素水平（雌二醇、雌三醇、雌酮、卵泡刺激素、促黄体素、孕酮、催乳素、生长激素、皮质醇、5-羟色胺、肾上腺素、去甲肾上腺素、胰岛素、胰高血糖素、瘦素）和泌乳性能指标（乳产量、乳蛋白率、乳脂肪率、乳糖率、灰分含量）。对血清激素水平和泌乳性能进行典型相关分析：以泌乳性能各指标为X组变量,对应的综合变量为V;以血清激素水平为Y组变量,对应的综合变量为W;利用这两个综合变量之间的相关关系反映两组指标之间的整体相关性,探究血清激素水平与泌乳性能各指标之间的相关关系。[结果]在泌乳性能指标X组中,乳产量的变异程度最大,其次是乳脂肪率,乳糖率、灰分含量、乳蛋白率的变异系数较小;在血清激素水平指标Y组中,变异系数最大的是孕酮,其次是雌二醇,然后依次是促黄体素、去甲肾上腺素、卵泡刺激素、5-羟色胺、皮质醇、雌酮、催乳素、肾上腺素、胰岛素、雌三醇、生长激素、瘦素、胰高血糖素。血清激素水平内部变量间的相关性分析表明,雌三醇的血清水平与雌酮（r=0.88,P<0.001）、促黄体素（r=0.70,P<0.001）、催乳素（r=0.59,P<0.001）显著正相关。泌乳性能与血清激素水平的典型相关分析表明,乳蛋白率与雌三醇的血清水平有较大的相关性。[结论]阿拉善双峰驼泌乳初期的乳蛋白率与雌三醇、雌酮、促黄体素和催乳素的血清激素水平具有相关性。

关键词: 阿拉善双峰驼, 泌乳性能, 血清激素水平, 典型相关分析

Abstract: [Objective] The present study was conducted to assess the correlations between serum hormone levels and lactation performance in Alagxa Bactrian camels. [Method] A total of 65 Alagxa Bactrian camels with similar body conditions and parities in the early lactation stage were selected, and their serum hormone levels （estradiol, estriol, estrone, follicle-stimulating hormone, luteinizing hormone, progesterone, prolactin, growth hormone, cortisol, 5-hydroxytryptamine, epinephrine, norepinephrine, insulin, glucagon, leptin） as well as the lactation performance indicators （milk yield, milk protein rate, milk fat rate, lactose rate, ash content） were determined. Canonical correlation analysis between serum hormone levels and lactation performance was carried out: using lactation performance indicators as the X group variables, with V being the corresponding comprehensive variable; using serum hormone levels as the Y group variables, with W being the corresponding comprehensive variable; the overall correlation between the two groups of indicators were reflected by the correlation between the two comprehensive variables, and the correlations between serum hormone levels and various indicators of lactation performance were explored. [Result] In the X group of lactation performance indicators, the variation degree in the milk yield was the highest, followed by milk fat rate, while the coefficients of variation in lactose rate, ash content and milk protein rate were relatively small. In the Y group of serum hormone level indicators, progesterone had the highest coefficient of variation, followed by estradiol, luteinizing hormone, norepinephrine, follicle-stimulating hormone, 5-hydroxytryptamine, cortisol, estrone, prolactin, epinephrine, insulin, estriol, growth hormone, leptin and glucagon. The correlation analysis among the internal variables of serum hormone levels showed that serum levels of estriol were significantly positively correlated with those of estrone （r=0.88, P<0.001）, luteinizing hormone （r=0.70, P<0.001） and prolactin （r=0.59, P<0.001）. The canonical correlation analysis between lactation performance and serum hormone levels indicated strong correlation between milk protein rate and serum level of estriol. [Conclusion] The milk protein rate in the early lactation stage of Alagxa Bactrian camels is correlated with serum hormone levels of estriol, estrone, luteinizing hormone and prolactin.

Key words: Alagxa Bactrian camel, lactation performance, serum hormone level, canonical correlation analysis

中图分类号:

S824

道勒玛, 郭丽丽, 杜海波, 张文广, 曾亚英. 基于典型相关分析探究阿拉善双峰驼血清激素水平与泌乳性能的相关性[J]. 畜牧与饲料科学, 2023, 44(6): 88-93.

Daolema, GUO Lili, DU Haibo, ZHANG Wenguang, ZENG Yaying. Investigation of Correlations between Serum Hormone Levels and Lactation Performance in Alagxa Bactrian Camels Based on Canonical Correlation Analysis[J]. Animal Husbandry and Feed Science, 2023, 44(6): 88-93.

参考文献

[1] ZARRIN M, RIVEROS J L, AHMADPOUR A, et al.Camelids:New players in the international animal production context[J].Tropical Animal Health and Production,2020,52(3):903-913.
[2] 张瑾,李景芳,徐敏,等.双峰驼的泌乳性能及其影响因素[J].新疆畜牧业,2022,37(1):24-28.
[3] HO T M, ZOU Z, BANSAL N.Camel milk: A review of its nutritional value, heat stability, and potential food products[J].Food Research International, 2022,153:110870.DO I:10.1016/j.foodres.2021.110870.
[4] BENMEZIANE - DERRADJI F.Evaluation of camel milk: Gross composition-A scientific overview[J].Tropical Animal Health and Production,2021,53(2):308.
[5] BEHROUZ S, SAADAT S, MEMARZIA A, et al.The antioxidant, anti-inflammatory and immunomodulatory ef-fects of camel milk[J].Frontiers in Immunology,2022,13:855342.
[6] BAUMAN D E, MATHER I H, WALL R J, et al.Major advances associated with the biosynthesis of milk[J].Journal of Dairy Science,2006,89(4):1235-1243.
[7] LIEW C C, MA J, TANG H C, et al.The peripheral blood transcriptome dynamically reflects system wide biology: A potential diagnostic tool[J].Journal of Laboratory and Clinical Medicine,2006,147(3):126-132.
[8] CONKLIN S E, KNEZEVIC C E.Advancements in the gold standard: Measuring steroid sex hormones by mass spectrometry[J].Clinical Biochemistry,2020,82:21-32.
[9] PAL P, GHOSH S, GREWAL S, et al.Role of hormones in persistency of lactation: A review[J].Journal of Entomology and Zoology Studies,2019,7(2):677-686.
[10] HOFFMANN B, SCHAMS D, GIMÉNEZ T, et al. Changes of progesterone, total oestrogens, corticosteroids, prolactin and LH in bovine peripheral plasma around parturition with special reference to the effect of exogenous corticoids and a prolactin inhibitor respectively[J].Acta Endocrinologica,1973,73(2):385-395.
[11] KIM Y J.Pivotal roles of prolactin and other hormones in lactogenesis and the nutritional composition of human milk[J].Clinical and Experimental Pediatrics,2020,63(8):312-313.
[12] SHETH N A, TIKEKAR S S, RANADIVE K J, et al.Influence of bromoergocryptine on estrogen-modulated prolactin receptors of mouse mammary gland[J].Molecular and Cellular Endocrinology,1978,12(2):167-176.
[13] MOSHEL Y, RHOADS R E, BARASH I.Role of amino acids in translational mechanisms governing milk protein synthesis in murine and ruminant mammary epithelial cells[J].Journal of Cellular Biochemistry,2006,98(3):685-700.
[14] KADOKAWA H.Discovery of new receptors regulating luteinizing hormone and follicle-stimulating hormone secretion by bovine gonadotrophs to explore a new paradigm for mechanisms regulating reproduction[J].Journal of Reproduction and Development,2020,66(4):291-297.
[15] AKERS R M.Major advances associated with hormone and growth factor regulation of mammary growth and lactation in dairy cows[J].Journal of Dairy Science,2006,89(4):1222-1234.
[16] 李有梅,梁珣.典型相关分析综述[J].中国计量大学学报,2017(1):113-118.
[17] NEVILLE M C, MCFADDEN T B, FORSYTH I.Hormonal regulation of mammary differentiation and milk secretion[J].Journal of Mammary Gland Biology and Neoplasia,2002,7(1):49-66.
[18] 黄兆春,霍应栋,赵喜棪,等.小尾寒羊不同乳腺发育时期7种激素分泌规律[J].甘肃农业大学学报,2023,58(2):9-15.
[19] CAIAZZA F, RYAN E J, DOHERTY G, et al.Estrogen receptors and their implications in colorectal carcinogenesis[J].Frontiers in Oncology,2015,5:19.
[20] ADGENT M A, UMBACH D M, ZEMEL B S, et al.A longitudinal study of estrogen-responsive tissues and hormone concentrations in infants fed soy formula[J].The Journal of Clinical Endocrinology and Metabolism,2018,103(5):1899-1909.
[21] DELBECCHI L, MILLER N, PRUD′HOMME C, et al. 17β-estradiol reduces milk synthesis and increases stanniocalcin gene expression in the mammary gland of lactating cows[J].Livestock Production Science,2005,98(1):57-66.
[22] 杨建英. 大豆黄酮对不同泌乳期奶牛产奶量、乳成分的影响及相关作用机制的研究[D].郑州:河南农业大学,2003.
[23] 艾晓杰,吴晓林,朱勇琪,等.大豆黄酮对荷斯坦牛围产期某些代谢激素的影响[J].中国奶牛,2004(5):12-14.
[24] 金亚亚,李大彪,孙梅,等.组合添加雌激素和催乳素对奶牛乳腺上皮细胞酪蛋白合成的影响[J].中国细胞生物学学报,2021,43(12):2316-2325.
[25] LIN M, WANG N, YAO B, et al.Quercetin improves postpartum hypogalactia in milk-deficient mice via stimulating prolactin production in pituitary gland[J].Phytotherapy Research,2018,32(8):1511-1520.
[26] NI Y F, CHEN Q Q, CAI J F, et al.Three lactation-related hormones: Regulation of hypothalamus-pituitary axis and function on lactation[J].Molecular and Cellular Endocrinology,2021,520:111084.

基于典型相关分析探究阿拉善双峰驼血清激素水平与泌乳性能的相关性

Investigation of Correlations between Serum Hormone Levels and Lactation Performance in Alagxa Bactrian Camels Based on Canonical Correlation Analysis

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 13

编辑推荐

Metrics

本文评价

[1]	张俊丽, 侯鹏霞, 梁小军. 南瓜籽壳对不同生长阶段西杂肉牛生长性能、血清生化和免疫指标及激素水平的影响[J]. 畜牧与饲料科学, 2024, 45(1): 20-24.
[2]	李晓燕, 王新, 李红, 杨云洪, 李东全, 车太龙. 日粮中添加不同水平氧化镁对奶牛泌乳性能、血清镁含量及尿液pH值的影响[J]. 畜牧与饲料科学, 2022, 43(5): 74-78.
[3]	杨永青, 王文曦, 李国银, 张欣昕, 聂晶, 莎娜, 史培. 阿拉善双峰驼及驼乳、驼肉研究概述[J]. 畜牧与饲料科学, 2021, 42(2): 109-113.
[4]	刘建忠,项性龙,郑应家,胡芳,刘金银,石俭省. 倍肽德酵母培养物对母猪泌乳性能的影响试验研究[J]. 畜牧与饲料科学, 2018, 39(12): 41-44.
[5]	李宏亮,韩吉雨,何志辉,刘琪,郝建,李俊良,兰儒冰,穆洋,宋丽华. 高寒地区秋、冬季荷斯坦奶牛补饲优质饲料对采食量、泌乳性能和乳房炎发病率的影响[J]. 畜牧与饲料科学, 2016, 37(3): 27-27.
[6]	许小楠,李忠莉,于德斌,武瑞. 贝尔美对奶牛泌乳性能影响的研究[J]. 畜牧与饲料科学, 2016, 37(1): 37-37.
[7]	道勒玛,斯琴图雅,张强,那顺. 补饲蛋白质饲料与能量饲料对阿拉善双峰驼产乳量的影响[J]. 畜牧与饲料科学, 2014, 35(11): 38-38.
[8]	张巧娥,杨库. 不同形式的蛋氨酸对奶牛泌乳性能的影响[J]. 畜牧与饲料科学, 2007, 28(2): 17-17.
[9]	王志新,张玉. 家兔泌乳性能的测定及产仔行为的观察[J]. 畜牧与饲料科学, 2006, 27(2): 55-55.
[10]	沈美英. 热应激情况下奶牛日粮中添加铬螯合物对奶牛泌乳性能和血相参数的影响[J]. 畜牧与饲料科学, 2006, 27(1): 17-17.
[11]	沈美英. 农场后备青年母牛的管理[J]. 畜牧与饲料科学, 2005, 26(5): 20-20.
[12]	沈美英. 奶牛围产期饲喂甘油对血浆代谢物和泌乳性能的影响[J]. 畜牧与饲料科学, 2005, 26(3): 19-19.
[13]	呼和巴特尔,白音巴图,巴勇舸,郭媛华,社跃峰. “蝇蛆粉”治疗骆驼阴道蝇蛆病的试验观察[J]. 畜牧与饲料科学, 1995, 16(2): 31-31.