Abstract: Combining the teaching contents and characteristics of Technology of Prevention and Treatment of Common Diseases of Livestock and Poultry in higher vocational college and the related teaching practice under the background of freshmen′s professional experience,this article expounds the exploration and experience of the key skill cultivating of Technology of Prevention and Treatment of Common Disease of Livestock and Poultry in Chongqing Three Gorges Vocational College from the following aspects:establishment of teaching materials,improvement of teaching contents,methods and means,stimulation of students′interests,emphasis on operational training,and reform of examination methods,in hoping to promoting the teaching quality improvement of this course.