Abstract: The blood indices of Clarias leather were determined.The erythrocyte density and leukocyte density were（29.04±2.12）×106 ind/mm3 and（1.21±0.85）×104 ind/mm3 respectively.The hemoglobin content was（7.64±0.69）g/L and the erythrocyte osmotic fragility was（0.46±0.03）%.The hematocrit was（36.69±0.99）% and the erythrocyte sedimentation rate was（3.40±0.56）mm/h.Through the smear observation of peripheral blood in Clarias leather,erythrocytes,thrombocytes,lymphocytes,neutrophils and monocytes were recognized.But eosinophilic granulocytes and basophilic granulocytes were not found.And the percentages of thrombocytes,large lymphocyte,small lymphocytes,neutrophils and monocytes in total leucocytes were （3.43±0.74）%,（4.36±0.65）%,（60.09±1.35）%,（16.62±1.29）% and（14.60±0.79）% respectively.Besides,some immature red blood cells could also be observed on the smears.The hemocytopoiesis processes of blood cells in liver,spleen,pronephros and kidney were observed and measured.The results showed that pronephros,kidney and spleen of Clarias leather could produce all kinds of blood cells and they were main hematopoietic organs.