Abstract: Coccidiosis is one of the most common disease and the most serious disease in rabbits. So far anticoccidial drugs are still used for the treatment and prevention of coccidiosis at home and abroad. So far China has not yet developed a commercial rabbit coccidiosis vaccine, and only a few scholars have developed rabbit coccidiosis vaccines at home and abroad. Research progress of live vaccine, subunit vaccine and genetic engineering vaccine on rabbit coccidiosis were reviewed in order to provide reference for study on rabbit coccidium vaccine.