Abstract: The disinfection is an important epidemic prevention tache. Especially, more bacteria and viruses propagate in hot summer, so the importance should be attached to the disinfection of breeding farms. The influencing factors of the disinfection effects were the selection, usage methods of disinfectants and the interval time of disinfection, etc. Some common unreasonable and nonstandard drug-use phenomena in the disinfection process of breeding farms in hot season were introduced. And some reasonable drug-use methods were proposed, in order to guide the reasonable use of disinfectants in the production process in the breeding farms, do good common disinfection jobs and provide basis for the production in breeding farms.