Abstract: The creep feed is prepared to substitute the whole milk and has the function of promoting the growth and development of piglets and improving their weaning weight. It can help the piglets learn to feed during lactation. This article briefly described the efficacy, processing technology and feed morphology of creep feed, and reviewed the effect of antimicrobial-free creep feed on growth and development of piglets, in hoping to provide references for the research and application of creep feed in piglets rearing.