德国肉用美利奴羊全基因组选择信号检测

doi:10.12160/j.issn.1672-5190.2019.07.001

Abstract

Abstract: The aim of this study was to assess the genome selection signature in German Merino mutton sheep. The high-density SNPs chip for sheep and iHS method was used to detect the genome selection signature, and the potential selection genes was revealed via bioinformatical analysis. The selection signature detection results indicated that a total of 220 genomic segments with selection signature were found within the genome-wide range. These segments were closely related to 895 candidate genes. Gene enrichment results indicated that these genes were mainly involved in protein translation, skeletal development, biosynthesis regulation, muscle organ development, retinoic acid receptor activity, transcription factor binding and ribosome components. The results obtained in this study provide a reference for making full use of the breeding value of German Merino mutton sheep and efficiently carrying out population improvement work for this breed of sheep.

Key words: German Merino mutton sheep, selection signature, high-density SNPs chip

CLC Number:

S826.862

LIU Jia-sen, LI Yun-hua, WANG Run-yuan, JIANG Shou-jun, MA Wan-shan, WANG Li-yong. Genome-wide Detection of Selection Signature in German Merino Mutton Sheep[J]. Animal Husbandry and Feed Science, 2019, 40(7): 1-7.

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Genome-wide Detection of Selection Signature in German Merino Mutton Sheep

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