Animal Husbandry and Feed Science ›› 2009, Vol. 30 ›› Issue (6): 1-1.doi: 10.12160/j.issn.1672-5190.2009.06.001

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Effect of Dimethyl Sulfoxide on The Activity of Tyrosinase

CHEN Yi, TANG Hong-min, FAN Ming-tao (1.College of Food Science and Engineering, Northwest A & F University, Yangling 712100, China;2.School of Chemistry and Environmental Science, Guizhou University for Nationalities, Guiyang 550025,China)   

  • Online:2009-06-20 Published:2009-06-20

Abstract: The effect of dimethyl sulfoxide on the activity of mushroom tyrosinase was carried out by enzymological kinetic method with the condition of 25℃ and pH 6.8 phosphate solution buffer. The results showed that the diphenolase activity increased with increase of of DMSO based on the prior volume fraction was less than 25 % in the reaction system. Contrarily, the activity of diphenolase sharply decreased. The action mechanism of DMSO was explored in this paper, which provided scientific basis for development of medicines to treat the diseases associated with tyrosinase-induced.

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