Animal Husbandry and Feed Science ›› 2019, Vol. 40 ›› Issue (9): 86-88.doi: 10.12160/j.issn.1672-5190.2019.09.018

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Research Progress on Anti-tumor Pharmacological Effects and Mechanism of Isoorientin

ZHANG Tong, ZHANG Yu, WANG Shi-nong, WANG Jia-ru, LUO Ying-hua, JIN Cheng-hao   

  1. College of Life Science and Technology,Heilongjiang Bayi Agricultural University,Daqing 163319, China
  • Received:2019-04-28 Online:2019-09-30 Published:2019-12-17

Abstract: Isoorientin is a compound containing flavonoid active ingredients extracted from plants. Studies have shown that isoorientin has a variety of pharmacological effects, not only has antioxidant, anti-inflammatory and anti-viral activities, but also has good anti-tumor activity. Isoorientin exerts anti-tumor role by interfering with the proliferation of cancer cells, inducing apoptosis of cancer cells, regulating the level of reactive oxygen species, inducing autophagy of cancer cells, and hindering the invasion and metastasis of cancer cells. This article reviewed the research progress of anti-tumor effect and mechanism of isoorientin.

Key words: isoorientin, anti-tumor, cell apoptosis, cell autophagy, cell proliferation

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