动植物miRNA实现跨物种基因调控的研究进展

doi:10.12160/j.issn.1672-5190.2022.02.002

Abstract

Abstract: In recent years, researchers have discovered that animals contain a type of non-self-derived miRNA, which were always ingested by food and have regulatory functions in animals. These findings may provide some theoretical foundations for extracting specific compounds from plants as additives or investigating the mechanisms underlying the therapeutic role of Chinese herbal medicine. They also broaden the research scope of exogenous animal and plant miRNA. From the aspects of formation process, structural characteristics, stability post cross-kingdom, tissue-specific expression, target gene binding mode, biological function, and cross-kingdom regulation, this paper systematically illustrated the mechanisms underlying the cross-kingdom gene regulation of animal and plant miRNA, reviewed corresponding research progress, and forecasted future research directions and applications of animal and plant miRNA, in hoping to serve as a guide for the development and utilization of miRNA in disease treatment and nutritional supplementation.

Key words: miRNA, cross-kingdom, gene regulation, stability post cross-kingdom, tissue specificity

CLC Number:

Q522

MENG Gui-zhi, LIU Bao-bao, LI Ya-hui, MA Yan-fen, WANG Xing-ping, MA Yun, CAI Xiao-yan. Advances in Cross-kingdom Regulation of Gene Expression Via miRNA in Animal and Plant[J]. Animal Husbandry and Feed Science, 2022, 43(2): 7-13.

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Advances in Cross-kingdom Regulation of Gene Expression Via miRNA in Animal and Plant

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