植物miR159靶向MYB基因家族的调控作用及其跨界调控哺乳动物生理功能的研究进展

doi:10.12160/j.issn.1672-5190.2022.05.008

Abstract

Abstract:

Plant miR159 has been found to play a key role in a variety of physiological processes such as growth and development, metabolism, response to stress, and pathogen defense in plant by targeting MYB gene family. It has also been proved to have a cross-kingdom regulative role in mammalian physiological functions, such as inhibition of tumor growth, improvement of energy metabolism, anti-oxidative stress and regulation of immunity. This paper described the involvement of miR159 in regulation of nutritional growth, response to stress, flowering and fruit development in a variety of plants, and reviewed the cross-kingdom regulative role of exogenous plant miR159 in mammalian physiological functions and breast cancer, in hoping to provide references for the subsequent study on the regulative network and cross-kingdom regulative mechanism of plant miR159.

Key words: miR159, MYB family, cross-kingdom regulation, physiological functions

CLC Number:

S814.2

DUAN Hong-juan, MENG Gui-zhi, LIU Bao-bao, JIA Jing-ying, MA Yan-fen, MA Yun, CAI Xiao-yan. Advances in Regulative Role of Plant miR159 Targeting MYB Gene Family and Its Cross-kingdom Regulation in Mammalian Physiological Functions[J]. Animal Husbandry and Feed Science, 2022, 43(5): 48-54.

0
/ / Recommend

Add to citation manager EndNote|Reference Manager|ProCite|BibTeX|RefWorks

URL: https://journal30.magtechjournal.com/xmysl/EN/10.12160/j.issn.1672-5190.2022.05.008

https://journal30.magtechjournal.com/xmysl/EN/Y2022/V43/I5/48

Figures/Tables 1

References 71

[1]	张源, 李新月. 脂多糖抑制牙周膜细胞骨唾液酸蛋白表达中微小RNA的筛选与验证[J]. 口腔医学研究, 2020, 36(5):477-480. doi: 10.13701/j.cnki.kqyxyj.2020.05.018
[2]	LLAVE C, KASSCHAU K D, RECTOR M A, et al. Endogenous and silencing-associated small RNAs in plants[J]. The Plant Cell, 2002, 14(7):1605-1619. doi: 10.1105/tpc.003210
[3]	王浩. 矮牵牛MIR159基因敲除对生长发育的影响[D]. 重庆: 西南大学, 2019.
[4]	CHEN S Y, SU M H, KREMLING K A, et al. Identification of miRNA-eQTLs in maize mature leaf by GWAS[J]. BMC Genomics, 2020, 21(1):689. doi: 10.1186/s12864-020-07073-0
[5]	YANG Q, LIU S B, HAN X N, et al. Integrated transcriptome and miRNA analysis uncovers molecular regulators of aerial stem-to-rhizome transition in the medical herb Gynostemma pentaphyllum[J]. BMC Genomics, 2019, 20(1):865. doi: 10.1186/s12864-019-6250-8 pmid: 31730459
[6]	BARRERA-ROJAS C H, OTONI W C, NOGUEIRA F T S. Shaping the root system: The interplay between miRNA regulatory hubs and phytohormones[J]. Journal of Experimental Botany, 2021, 72(20):6822-6835. doi: 10.1093/jxb/erab299
[7]	GUO H S, XIE Q, FEI J F, et al. MicroRNA directs mRNA cleavage of the transcription factor NAC1 to downregulate auxin signals for Arabidopsis lateral root development[J]. The Plant Cell, 2005, 17(5):1376-1386. doi: 10.1105/tpc.105.030841
[8]	WANG H, LI Y, CHERN M, et al. Suppression of rice miR168 improves yield, flowering time and immunity[J]. Nature Plants, 2021, 7(2):129-136. doi: 10.1038/s41477-021-00852-x pmid: 33594262
[9]	SONG X W, LI Y, CAO X F, et al. MicroRNAs and their regulatory roles in plant-environment interactions[J]. Annual Review of Plant Biology, 2019, 70:489-525. doi: 10.1146/annurev-arplant-050718-100334 pmid: 30848930
[10]	胡志刚, 曹俊婷, 张建勤, 等. miRNA对畜禽肌肉生长发育调控的研究进展[J]. 中国兽医学报, 2021, 41(6):1204-1209.
[11]	BARTEL D P. MicroRNAs: Genomics, biogenesis, mechanism, and function[J]. Cell, 2004, 116(2):281-297. doi: 10.1016/s0092-8674(04)00045-5 pmid: 14744438
[12]	ALLEN R S, LI J Y, STAHLE M I, et al. Genetic analysis reveals functional redundancy and the major target genes of the Arabidopsis miR159 family[J]. Proceedings of the National Academy of Sciences, 2007, 104(41):16371-16376. doi: 10.1073/pnas.0707653104
[13]	KIDNER C A, MARTIENSSEN R A. The developmental role of microRNA in plants[J]. Current Opinion in Plant Biology, 2005, 8(1):38-44. doi: 10.1016/j.pbi.2004.11.008 pmid: 15653398
[14]	CHAVEZ MONTES R A, ROSAS-CÁRDENAS F F, DE PAOLI E, et al. Sample sequencing of vascular plants demonstrates widespread conservation and divergence of microRNAs[J]. Nature Communications, 2014, 5(1):3322. doi: 10.1038/ncomms4322
[15]	PALATNIK J F, ALLEN E, WU X L, et al. Control of leaf morphogenesis by microRNAs[J]. Nature, 2003, 425(6955):257-263. doi: 10.1038/nature01958
[16]	李波娣. 大豆miR159家族的鉴定及miR159e功能初探[D]. 广州: 华南农业大学, 2018.
[17]	MALLORY A C, VAUCHERET H. Functions of microRNAs and related small RNAs in plants[J]. Nature Genetics, 2006, 38(6):31-36.
[18]	杨晶婷, 余艳, 高晓蓉, 等. MYB类转录因子调控植物耐逆机制的研究进展[J]. 杭州师范大学学报(自然科学版), 2021, 20(6):621-627.
[19]	王静文, 谭萌萌, 孙绍营, 等. 基于转录组信息的细叶百合MYB转录因子家族分析[J/OL]. 分子植物育种, 2021,1-12 [2021-12-14] https://kns.cnki.net/kcms/detail/46.1068.S.20211213.1536.009.htmlhttps://kns.cnki.net/kcms/detail/46.1068.S.20211213.1536.009.html.
[20]	段俊枝, 李莹, 冯丽丽, 等. MYB转录因子在水稻抗逆基因工程中的应用进展[J]. 江苏农业科学, 2021, 49(21):46-53.
[21]	葛金涛, 王丽丽, 赵统利, 等. 葡萄miR159家族生物信息学分析及靶基因预测分析[J]. 江西农业学报, 2018, 30(2):21-25.
[22]	XUE T, LIU Z H, DAI X H, et al. Primary root growth in Arabidopsis thaliana is inhibited by the miR159 mediated repression of MYB33, MYB65 and MYB101[J]. Plant Science, 2017, 262:182-189. doi: 10.1016/j.plantsci.2017.06.008
[23]	黎猛, 陈跃, 胡凤荣. miR159-GAMYB途径调控植物生长发育的研究进展[J]. 生物技术通报, 2021, 37(9):234-247. doi: 10.13560/j.cnki.biotech.bull.1985.2021-0028
[24]	ALLEN R S, LI J Y, ALONSO-PERAL M M, et al. MicroR159 regulation of most conserved targets in Arabidopsis has negligible phenotypic effects[J]. Silence, 2010, 1(1):18. doi: 10.1186/1758-907X-1-18
[25]	LI W F, ZHANG S G, HAN S Y, et al. Regulation of LaMYB33 by miR159 during maintenance of embryogenic potential and somatic embryo maturation in Larix kaempferi (Lamb.) Carr[J]. Plant Cell, Tissue and Organ Culture, 2013, 113(1):131-136. doi: 10.1007/s11240-012-0233-7
[26]	CSUKASI F, DONAIRE L, CASANAL A, et al. Two strawberry miR159 family members display developmental‐specific expression patterns in the fruit receptacle and cooperatively regulate Fa‐GAMYB[J]. The New Phytologist, 2012, 195(1):47-57. doi: 10.1111/j.1469-8137.2012.04134.x
[27]	蒋有琦. miR159调节植物抗旱分子机理研究[D]. 杭州: 浙江农林大学, 2017.
[28]	WANG Y, SUN F, CAO H, et al. TamiR159 directed wheat TaGAMYB cleavage and its involvement in anther development and heat response[J]. PloS One, 2012, 7(11):e48445. doi: 10.1371/journal.pone.0048445
[29]	LI X Y, BIAN H W, SONG D F, et al. Flowering time control in ornamental gloxinia (Sinningia speciosa) by manipulation of miR159 expression[J]. Annals of Botany, 2013, 111(5):791-799. doi: 10.1093/aob/mct034 pmid: 23404992
[30]	王梦琦, 解振强, 孙欣, 等. 葡萄miR159及其靶基因VvGAMYB在花发育过程中的作用分析[J]. 园艺学报, 2017, 44(6):1061-1072. doi: 10.16420/j.issn.0513-353x.2016-0816
[31]	ZHANG Y, ZHANG B, YANG T, et al. The GAMYB-like gene SlMYB33 mediates flowering and pollen development in tomato[J]. Horticulture Research, 2020, 7(1):133. doi: 10.1038/s41438-020-00366-1
[32]	邓因娇. Sly-miR159a调控番茄果实形状的机理研究[D]. 深圳: 深圳大学, 2020.
[33]	张博, 杨正福, LIM K J, 等. 山核桃miR159家族成员进化特性分析及功能研究[J]. 果树学报, 2021, 38(6):884-894.
[34]	AYA K, UEGUCHI-TANAKA M, KONDO M, et al. Gibberellin modulates anther development in rice via the transcriptional regulation of GAMYB[J]. The Plant Cell, 2009, 21(5):1453-1472. doi: 10.1105/tpc.108.062935
[35]	TSUJI H, AYA K, UEGUCHI‐TANAKA M, et al. GAMYB controls different sets of genes and is differentially regulated by microRNA in aleurone cells and anthers[J]. The Plant Journal, 2006, 47(3):427-444. doi: 10.1111/tpj.2006.47.issue-3
[36]	侯丹. 毛竹生殖器官发育相关 miRNA 挖掘与 miR159-GAMYB 途径对花药发育调控研究[D]. 北京: 中国林业科学研究院, 2018.
[37]	ZHENG Z H, REICHEL M, DEVESON I, et al. Target RNA secondary structure is a major determinant of miR159 efficacy[J]. Plant Physiology, 2017, 174(3):1764-1778. doi: 10.1104/pp.16.01898 pmid: 28515145
[38]	ZHENG Z, WANG N, JALAJAKUMARI M, et al. miR159 represses a constitutive pathogen defense response in tobacco[J]. Plant Physiology, 2020, 182(4):2182-2198. doi: 10.1104/pp.19.00786 pmid: 32041907
[39]	LEI P, QI N W, ZHOU Y, et al. Soybean miR159-GmMYB33 regulatory network involved in gibberellin-modulated resistance to Heterodera glycines[J]. International Journal of Molecular Sciences, 2021, 22(23):13172. doi: 10.3390/ijms222313172
[40]	AN F M, CHAN M T. Transcriptome-wide characterization of miRNA-directed and non-miRNA-directed endonucleolytic cleavage using Degradome analysis under low ambient temperature in Phalaenopsis aphrodite subsp. formosana[J]. Plant and Cell Physiology, 2012, 53(10):1737-1750. doi: 10.1093/pcp/pcs118
[41]	ZHAO P P, WANG F P, DENG Y J, et al. Sly‐miR159 regulates fruit morphology by modulating GA biosynthesis in tomato[J]. Plant Biotechnology Journal, 2022, 20(5):833-845. doi: 10.1111/pbi.v20.5
[42]	LIU N, TU L X, TANG W X, et al. Small RNA and degradome profiling reveals a role for mi RNAs and their targets in the developing fibers of Gossypium barbadense[J]. The Plant Journal, 2014, 80(2):331-344. doi: 10.1111/tpj.12636
[43]	LUO X Y, GAO Z H, SHI T, et al. Identification of miRNAs and their target genes in peach (Prunus persica L.) using high-throughput sequencing and degradome analysis[J]. PLoS One, 2013, 8(11):e79090. doi: 10.1371/journal.pone.0079090
[44]	SUN F L, GUO G H, DU J K, et al. Whole-genome discovery of miRNAs and their targets in wheat (Triticum aestivum L.)[J]. BMC Plant Biology, 2014, 14(1):142. doi: 10.1186/1471-2229-14-142
[45]	ZHAO Y F, WEN H L, TEOTIA S, et al. Suppression of microRNA159 impacts multiple agronomic traits in rice (Oryza sativa L.)[J]. BMC Plant Biology, 2017, 17(1):215. doi: 10.1186/s12870-017-1171-7
[46]	SINGROHA G, SHARMA P, SUNKUR R. Current status of microRNA‐mediated regulation of drought stress responses in cereals[J]. Physiologia Plantarum, 2021, 172(3):1808-1821. doi: 10.1111/ppl.v172.3
[47]	MILLAR A A, LOHE A, WONG G. Biology and function of miR159 in plants[J]. Plants, 2019, 8(8):255. doi: 10.3390/plants8080255
[48]	陈永超, 齐怀廷, 王小晶, 等. 田菁茎瘤固氮根瘤菌对小麦叶组织的促生作用研究[J]. 西北植物学报, 2016, 36(7):1383-1390.
[49]	XIA X L, SHAO Y F, JIANG J F, et al. MicroRNA expression profile during aphid feeding in chrysanthemum (Chrysanthemum morifolium)[J]. PLoS One, 2015, 10(12):e0143720. doi: 10.1371/journal.pone.0143720
[50]	彭廷, 文慧丽, 赵亚帆, 等. 盐、干旱胁迫下水稻相关miRNA的鉴定及表达分析[J]. 华北农学报, 2018, 33(2):20-27. doi: 10.7668/hbnxb.2018.02.004
[51]	XU F, LIU Q, CHEN L Y, et al. Genome-wide identification of soybean microRNAs and their targets reveals their organ-specificity and responses to phosphate starvation[J]. BMC Genomics, 2013, 14:66. doi: 10.1186/1471-2164-14-66 pmid: 23368765
[52]	GOCAL G F W, SHELDON C C, GUBLER F, et al. GAMYB-like genes, flowering, and gibberellin signaling in Arabidopsis[J]. Plant Physiology, 2001, 127(4):1682-1693. doi: 10.1104/pp.010442
[53]	ACHARD P, HERR A, BAULCOMBE D C, et al. Modulation of floral development by a gibberellin-regulated microRNA[J]. Development, 2004, 131(14): 3357-3365. doi: 10.1242/dev.01206 pmid: 15226253
[54]	ALONSO-PERAL M M, LI J Y, LI Y J, et al. The microRNA159-regulated GAMYB-like genes inhibit growth and promote programmed cell death in Arabidopsis[J]. Plant Physiology, 2010, 154(2):757-771. doi: 10.1104/pp.110.160630
[55]	REYES J L, CHUA N H. ABA induction of miR159 controls transcript levels of two MYB factors during Arabidopsis seed germination[J]. The Plant Journal, 2007, 49(4):592-606. doi: 10.1111/j.1365-313X.2006.02980.x
[56]	张安妮, 曹红星, 陈萍, 等. 小RNA测序揭示miRNAs在油棕合子胚发育中的作用[J]. 热带作物学报, 2022, 43(1):19-26.
[57]	DA SILVA E M, SILVA G, BIDOIA D B, et al. microRNA159-targeted SlGAMYB transcription factors are required for fruit set in tomato[J]. The Plant Journal, 2017, 92(1):95-109. doi: 10.1111/tpj.2017.92.issue-1
[58]	ZHANG L, HOU D, CHEN X, et al. Exogenous plant MIR168a specifically targets mammalian LDLRAP1: Evidence of cross-kingdom regulation by microRNA[J]. Cell Research, 2012, 22(1):273-274. doi: 10.1038/cr.2011.174
[59]	CHIN A R, FONG M Y, SOMLO G, et al. Cross-kingdom inhibition of breast cancer growth by plant miR159[J]. Cell Research, 2016, 26(2):217-228. doi: 10.1038/cr.2016.13 pmid: 26794868
[60]	WEBER J A, BAXTER D H, ZHANG S L, et al. The microRNA spectrum in 12 body fluids[J]. Clinical Chemistry, 2010, 56(11):1733-1741. doi: 10.1373/clinchem.2010.147405 pmid: 20847327
[61]	MORI M A, LUDWIG R G, GARCIA-MARTIN R, et al. Extracellular miRNAs:From biomarkers to mediators of physiology and disease[J]. Cell Metabolism, 2019, 30(4):656-673. doi: 10.1016/j.cmet.2019.07.011
[62]	LIU L, LU H, SHI R X, et al. Synergy of peptide-nucleic acid and spherical nucleic acid enabled quantitative and specific detection of tumor exosomal microRNA[J]. Analytical Chemistry, 2019, 91(20):13198-13205. doi: 10.1021/acs.analchem.9b03622 pmid: 31553171
[63]	LUO Y, WANG P J, WANG X, et al. Detection of dietetically absorbed maize-derived microRNAs in pigs[J]. Scientific Reports, 2017, 7:645. doi: 10.1038/s41598-017-00488-y pmid: 28381865
[64]	SALEH M C, VAN RIJ R P, HEKELE A, et al. The endocytic pathway mediates cell entry of dsRNA to induce RNAi silencing[J]. Nature Cell Biology, 2006, 8(8):793-802. doi: 10.1038/ncb1439
[65]	DUXBURY M S, ASHLEY S W, WHANG E E. RNA interference: A mammalian SID-1 homologue enhances siRNA uptake and gene silencing efficacy in human cells[J]. Biochemical and Biophysical Research Communications, 2005, 331(2):459-463. pmid: 15850781
[66]	ELHASSAN M O, CHRISTIE J, DUXBURY M S. Homo sapiens systemic RNA interference-defective-1 transmembrane family member 1 (SIDT1) protein mediates contact-dependent small RNA transfer and microRNA-21-driven chemoresistance[J]. The Journal of Biological Chemistry, 2012, 287(8):5267-5277. doi: 10.1074/jbc.M111.318865
[67]	CHEN Q, ZHANG F, DONG L, et al. SIDT1-dependent absorption in the stomach mediates host uptake of dietary and orally administered microRNAs[J]. Cell Research, 2021, 31(3):247-258. doi: 10.1038/s41422-020-0389-3
[68]	彭朦媛, 王颖芳. 植物microRNA跨界调控哺乳动物基因表达研究进展[J]. 广东药科大学学报, 2019, 35(5):714-718.
[69]	LIU J C, WANG F, SONG H Z, et al. Soybean-derived gma-miR159a alleviates colon tumorigenesis by suppressing TCF7/MYC in mice[J]. The Journal of Nutritional Biochemistry, 2021, 92:108627. doi: 10.1016/j.jnutbio.2021.108627
[70]	YU W Y, CAI W, YING H Z, et al. Exogenous plant gma-miR-159a, identified by miRNA library functional screening, ameliorated hepatic stellate cell activation and inflammation via inhibiting GSK-3β-Mediated pathways[J]. Journal of Inflammation Research, 2021, 14:2157-2172. doi: 10.2147/JIR.S304828
[71]	彭朦媛. 人参水煎剂及其microRNA对气虚疲劳小鼠的干预和跨界调控作用研究[D]. 广州: 广东药科大学, 2020.

Advances in Regulative Role of Plant miR159 Targeting MYB Gene Family and Its Cross-kingdom Regulation in Mammalian Physiological Functions

RichHTML

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

Figures/Tables 1

References 71

Related Articles 2

Recommended Articles

Metrics

Comments

[1]	WU Zi-xian, LI Yun-hua, ZHANG Bin, ZHANG Jun, ZHAO Yan-hong, LIU Jia-sen. Research Advances on Physiological Functions of Platelet-derived Growth Factor A [J]. Animal Husbandry and Feed Science, 2021, 42(4): 49-53.
[2]	. Physiological Functions and Efficacy of Aloe Components [J]. Animal Husbandry and Feed Science, 2012, 33(7): 8-8.