沙棘果实营养成分、药理作用研究进展

doi:10.12190/j.issn.2096-1197.2026.01.10

Abstract

Abstract: Sea buckthorn fruit is rich in nutritional components and exhibits antioxidant,anti-inflammatory,antitumor,hypolipidemic,immunoenhancing and other effects. This review summarizes phenolic acids,flavonoids,organic acids,vitamins and other nutritional components of sea buckthorn fruit,and analyzes their pharmacological effects on the cardiovascular,hematological,immune,and digestive systems,aiming to provide a reference for further exploration of the comprehensive value of sea buckthorn fruit and the full utilization of sea buckthorn fruit resources.

Key words: Sea buckthorn fruit, Nutritional components, Pharmacological effects, Research progress

CLC Number:

S793.6

WANG Qi, ZHU Lin, WANG Limin, ZHAO Hang, WANG Jiannan, WEI Dingyi, XIONG Qingshan, LIU Lianrong, DAI Xiaohua, HAN Juncheng. Research progress on the nutritional components and pharmacological effects of sea buckthorn fruit[J].Journal of Northern Agriculture, 2026, 54(1): 104-111.

References

[1] 王磊. 新疆沙棘产业发展现状分析及建议[J].新疆林业,2024(3):25-27.
[2] 周鹏程. 沙棘的生长习性及丰产栽培技术[J].特种经济动植物,2020,23(5):35-36.
[3] 贾江平. 沙棘的综合开发利用价值[J].内蒙古林业调查设计,2013,36(5):62.
[4] 赵胜春. 沙棘的生物学特性及种植方法[J].养殖技术顾问,2013(4):210.
[5] 陈奕璇,郭佳琦,关文强,等.沙棘综合开发利用研究进展[J].食品研究与开发,2023,44(19):201-207.
[6] 赵宏,于登君,汤威威,等.黄芪-百合-沙棘联用治疗阿尔茨海默病作用机制的网络药理学分析[J].中药新药与临床药理,2021,32(12):1817-1824.
[7] 苏婷婷. 四种沙棘果实营养与活性成分的比较及中国沙棘酚类物质的体外模拟消化[D].兰州:甘肃农业大学,2023.
[8] CRISTE A,URCAN A C,BUNEA A,et al.Phytochemical composition and biological activity of berries and leaves from four Romanian sea buckthorn(Hippophae rhamnoides L.) varieties[J].Molecules,2020,25(5):1170.
[9] 赵鑫丹,张东为,姜鑫,等.不同品种沙棘叶片和果实中酚酸类及黄酮类成分的比较[J].经济林研究,2024,42(4):247-256.
[10] ZADERNOWSKI R,NACZK M,CZAPLICKI S,et al.Composition of phenolic acids in sea buckthorn(Hippophae rhamnoides L.) berries[J].Journal of the American Oil Chemists′ Society,2005,82(3):175-179.
[11] RAFFO A,PAOLETTI F,ANTONELLI M.Changes in sugar,organic acid,flavonol and carotenoid composition during ripening of berries of three seabuckthorn(Hippophae rhamnoides L.)cultivars[J].European Food Research and Technology,2004,219(4):360-368.
[12] 赵卓婷. 不同沙棘黄酮的分析与抗氧化活性研究[D].哈尔滨:哈尔滨工业大学,2021.
[13] 李晓花. 沙棘有效成分动态变化研究[D].长春:吉林农业大学,2003.
[14] 戴达勇,杨英桂,贺万鑫.离子色谱法同时测定沙棘果粉中7种有机酸含量[J].理化检验(化学分册),2015,51(3):304-306.
[15] 李淑珍,武飞,陈月林,等.沙棘活性成分及功效研究进展[J].中国民族民间医药,2015,24(1):51-53.
[16] 石文堂. 沙棘的营养与药用研究[J].科技情报开发与经济,2003(9):166-167.
[17] 戈素芬,张东为,赵鑫丹,等.5个杂交沙棘品种果实营养成分比较分析[J].食品工业科技,2022,43(22):328-335.
[18] 张洋洋. 沙棘果解剖特征及Vc合成中关键酶活性研究[D].太原:山西大学,2017.
[19] 赵志强,朱叙丞,冯真颖,等.沙棘果多糖的理化特征及其体外抗氧化活性[J].食品工业科技,2023,44(13):30-38.
[20] 金婷. 沙棘多糖的提取纯化、结构鉴定及其抗氧化性的研究[D].哈尔滨:东北农业大学,2006.
[21] 钟运翠. 沙棘果渣中水溶性多糖的提取、分离、纯化及结构初探[D].大庆:黑龙江八一农垦大学,2009.
[22] 赵宏,张宇,柴桂芳,等.沙棘多糖的闪式提取工艺条件的优化[J].辽宁中医杂志,2015,42(2):364-366.
[23] SUKHBAATAR B,BORBAATAR B,ALTANGEREL B,et al.A dynamic study of some biological active compounds in the sea-buckthorn(Hippophae rhamnoides. L) berries[J].Journal of Pharmacy and Pharmacology,2017,5(6):366-373.
[24] 曹昕琪. 沙棘果油和沙棘籽油制备蛋黄酱及其稳定性研究[D].郑州:河南工业大学,2023.
[25] 许甜,吴萌,葛世辉,等.沙棘果、叶的研究进展[J].今日药学,2024,34(6):466-472.
[26] YANG B R,KALLIO H P.Fatty acid composition of lipids in sea buckthorn(Hippophae rhamnoides L.) berries of different origins[J].Journal of Agricultural and Food Chemistry,2001,49(4):1939-1947.
[27] 杨万政,曹秀君,李金淑,等.紫外分光光度法测定沙棘油中总类胡萝卜素方法改进[J].中央民族大学学报(自然科学版),2009,18(3):5-8.
[28] GUO R X,CHANG X,GUO C S,et al.Phenolic compounds,antioxidant activity,antiproliferative activity and bioaccessibility of sea buckthorn(Hippophae rhamnoides L.) berries as affected by in vitro digestion[J].Food & Function,2017,8(11):4229-4240.
[29] 吕兆林,袁玮琼,张柏林,等.沙棘果实中主要活性成分质量分布[J].北京林业大学学报,2021,43(1):144-152.
[30] 祁建宏,董芳旭.黄酮类化合物药理作用研究进展[J].北京联合大学学报,2020,34(3):89-92.
[31] 麻玉雯,马贺,王树林.超声波辅助提取沙棘有机酸及其成分分析[J].食品工业,2024,45(5):105-111.
[32] 马瑜红. 沙棘的有效成分及药理研究进展[J].四川生理科学杂志,2005,27(2):75-77.
[33] CHAUHAN A,SHIRKOT C K,KAUSHAL R,et al.Plant growth promoting rhizobacteria of medicinal plants in NW himalayas:current status and future prospects[M]//Plant-growth-promoting rhizobacteria(PGPR) and medicinal plants. Cham:Springer International Publishing,2014:381-412.
[34] YANG B R.Sugars,acids,ethyl β-d-glucopyranose and a methyl inositol in sea buckthorn(Hippophae rhamnoides)berries[J].Food Chemistry,2009,112(1):89-97.
[35] 吴紫洁,阮成江,李贺,等.12个沙棘品种的果实可溶性糖和有机酸组分研究[J].西北林学院学报,2016,31(4):106-112.
[36] 李靖,刘文昌,李付强,等.维生素E的生理功能及其在反刍动物生产中应用的研究进展[J].动物营养学报,2024,36(12):7573-7580.
[37] 于康英,宋绍征,鲍红光,等.B族维生素对抑郁症患者情绪和认知功能的影响[J].中国食品工业,2024(19):128-130.
[38] 李潇卓. 食品营养强化剂及其研究进展[J].现代食品,2016,22(11):16-17.
[39] 刘学静,史峻梅,朱丽业,等.维生素K₂的生物学功能研究进展[J].山东医药,2024,64(35):111-114.
[40] 孟庆龙,金莎,刘雅婧,等.植物多糖药理功效研究进展[J].食品工业科技,2020,41(11):335-341.
[41] 曾诚,杨晓艺,赵文惠.昆仑雪菊多糖预防急性及免疫性肝损伤[J].时珍国医国药,2017,28(11):2604-2607.
[42] 修伟业,黎晨晨,遇世友,等.类胡萝卜素生物学功能及提高其生物利用的研究进展[J].食品工业科技,2023,44(10):406-415.
[43] 董敏,张晶晶,田丁阳,等.中药沙棘的心血管药理作用研究进展[J].中医临床研究,2024,16(2):67-71.
[44] 张靖鹏,张得钧.基于网络药理-分子对接-体外抗氧化探究沙棘防治高血压的作用机制[J].实用中西医结合临床,2024,24(15):1-9.
[45] WANG L,WU H W,XIONG L,et al.Quercetin downregulates cyclooxygenase-2 expression and HIF-1α/VEGF signaling-related angiogenesis in a mouse model of abdominal aortic aneurysm[J].Biomed Research Internat-ional,2020,2020:9485398.
[46] ZHOU W N,OUYANG J,HU N,et al.Protective effect of two alkaloids from Hippophae rhamnoides Linn. against doxorubicin-induced toxicity in H9c2 cardiomyoblasts[J].Molecules,2021,26(7):1946.
[47] 崔慧玲,任永珍,邹元生,等.沙棘心血康口服液对犬冠脉流量和心肌耗氧的作用[J].沙棘,2000(3):35-37.
[48] 吴斯琴毕力格,包勒朝鲁,那生桑.沙棘药理作用研究进展[J].中国药业,2015,24(1):95-96.
[49] BASU M,PRASAD R,JAYAMURTHY P,et al.Anti-atherogenic effects of seabuckthorn(Hippophaea rhamnoides) seed oil[J].Phytomedicine,2007,14(11):770-777.
[50] 魏志成. 沙棘总黄酮对“气滞寒凝血瘀证”模型大鼠血管内皮损伤保护作用研究[D].成都:成都中医药大学,2018.
[51] OLAS B,KONTEK B,MALINOWSKA P,et al.Hippophae rhamnoides L. fruits reduce the oxidative stress in human blood platelets and plasma[J].Oxidative Medicine and Cellular Longevity,2016:4692486.
[52] STOCHMAL A,ROLNIK A,SKALSKI B,et al.Antiplatelet and anticoagulant activity of isorhamnetin and its derivatives isolated from sea buckthorn berries,measured in whole blood[J].Molecules,2022,27(14):4429.
[53] 艾孜古丽·木拉提.沙棘黄酮改善高热能膳食诱导小鼠糖脂代谢紊乱及认知障碍作用与机制研究[D].杨凌:西北农林科技大学,2022.
[54] 于淼. 黑龙江省沙棘资源开发及其药理作用探究[J].现代园艺,2024,47(14):122-124.
[55] 高山,刘暄,王晶,等.沙棘棕榈油酸提取物调节肌糖原合成及缓解2型糖尿病大鼠胰岛素抵抗的研究[J].中国食品添加剂,2017(11):51-57.
[56] HAO W J,HE Z Y,ZHU H Y,et al.Sea buckthorn seed oil reduces blood cholesterol and modulates gut microbiota[J].Food & Function,2019,10(9):5669-5681.
[57] 邹元生,聂勇,李新兰.沙棘果油对小鼠免疫调节的实验研究[J].国际沙棘研究与开发,2011,9(4):1-6.
[58] 凌娜,田海燕,高铭泽,等.沙棘多糖的制备、结构表征与药理活性研究进展[J].中国药学杂志,2024,59(9):757-767.
[59] 王萌,王子纯,黄京美,等.沙棘黄酮类物质提取纯化及功能活性研究进展[J].食品工业科技,2023,44(2):487-496.
[60] 杜新瑜. 饲粮中添加沙棘黄酮对肉兔生产性能、血液生化指标、抗氧化及免疫功能的影响[D].沈阳:沈阳农业大学,2023.
[61] 杜晶晶. 沙棘多糖抑菌、抗氧化及免疫活性的研究[D].大庆:黑龙江八一农垦大学,2011.
[62] JIE D,GAO T T,SHAN Z S,et al.Immunostimulating effect of polysaccharides isolated from Ma-Nuo-Xi decoction in cyclophosphamide-immunosuppressed mice[J].Inte-rnational Journal of Biological Macromolecules,2020,146:45-52.
[63] 刘秉春,云升,周二霞,等.沙棘黄酮联合树突状细胞治疗卵巢癌的研究[EB/OL].(2020-07-24).https://kns.cnki.net/kcms2/article/abstract?v=BkbJkO_np9NvWyJB2u_19kTuvycy4CZOsvXJ7NF0DtGRrMM-YglqdpvVv7-wyWSJMGnXui9i0ZPUdgA7sx_pMk3ApICAjbSW87t7bwXr0syiI5bNZUDsnR_WeIaXKk82VFa3iTFSTKcEsGHfVQEgR0Gb6aoPQ5EBL8roYO8P2Clgjau-b96YcQ==&uniplatform=NZKPT&language=CHS.
[64] 徐慧,闫莉,张雪松,等.沙棘黄酮基于NF-κB通路对哮喘的抑制作用机制的研究进展[J].现代医药卫生,2023,39(14):2452-2456.
[65] MULATI A,MA S B,ZHANG H B,et al.Sea-buckthorn flavonoids alleviate high-fat and high-fructose diet-induced cognitive impairment by inhibiting insulin resistance and neuroinflammation[J].Journal of Agricultural and Food Chemistry,2020,68(21):5835-5846.
[66] 王玉净,都治香,张霞,等.沙棘黄酮通过调控TLR4/NF-κB信号通路改善大鼠多囊卵巢综合征的作用[J].食品工业科技,2024,45(16):340-347.
[67] 包艳红,王强,张文龙,等.沙棘熊果酸通过调节线粒体-细胞色素c抑制酒精性肝病大鼠模型肝细胞凋亡的作用分析[J].临床肝胆病杂志,2023,39(7):1617-1626.
[68] 钱学射,金敬红.沙棘的药用研究与开发[J].中国野生植物资源,2015,34(6):68-72.
[69] 李清,马广礼,翟艺恒,等.沙棘多糖对小鼠酒精性肝炎和肠道屏障功能的治疗研究[J].食品工业科技,2025,46(8):351-361.
[70] 宋安康. 改性沙棘果油体外模拟消化及对肠道菌群调控效应研究[D].乌鲁木齐:新疆农业大学,2024.

Research progress on the nutritional components and pharmacological effects of sea buckthorn fruit

PDF (PC)

Like

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 14

Metrics

Comments

Recommended 0

[1]	HAN Chao, ZHU Yufei, LI Xinxin, PENG Zhidong, DU Lei, KANG Wenqin. Research progress on the antimicrobial and degradation functions of Streptomyces griseorubens and their mechanisms [J]. Journal of Northern Agriculture, 2025, 53(5): 78-87.
[2]	ZHANG Fuxin, HE Lianzhen, MA Nan. Research progress on nutritional and bioactive components of Fagopyrum esculentum [J]. Journal of Northern Agriculture, 2025, 53(3): 104-109.
[3]	YANG Huijie, LIU Zixin, HU Huiyong, ZHANG Gengjie. Research progress and prospects of the multifunctionality of cultivated land in China [J]. Journal of Northern Agriculture, 2025, 53(3): 110-121.
[4]	XU Haitao, MA Hongzhen, TIAN Zhenzhen, ZHANG Weiqiang, GUO Haibin, FENG Li, WANG Yanbin, JIANG Changjie, ZHEN Zhigao. Research progress on nutritional composition changes and processing utilization of peanut sprouts [J]. Journal of Northern Agriculture, 2025, 53(2): 109-118.
[5]	MA Qiang, DAI Lu, KE Na, ZHAO Yuxiang, CHEN Rong. Research progress on nutritional and bioactive components of Potentilla anserina [J]. Journal of Northern Agriculture, 2025, 53(2): 119-125.
[6]	MA Qiang, HE Lianzhen, MA Nan, WANG Shuai, DAI Lu. Research progress on millet nutritional components and its development and application [J]. Journal of Northern Agriculture, 2024, 52(6): 77-82.
[7]	XIONG Qingshan, WEI Dingyi, WEN Yaya, CHEN Qing, LIU Lianrong, LONG Chunhong, HAN Chao, DAI Xiaohua. Research progress on the chemical composition and pharmacological effects of sea buckthorn fruit [J]. Journal of Northern Agriculture, 2024, 52(3): 57-63.
[8]	JIN Qingting, HUANG Hongxing, JIANG Shun. Analysis of the research progress on crop pests and diseases identification based on Bibliometrics [J]. Journal of Northern Agriculture, 2023, 51(4): 122-134.
[9]	WANG Yuwen, YUAN Jingcheng, ZHONG Xin, YAO Xuhang, FAN Guangyu, LIU Yinghui, ZHAO Zhihai. Research progress in nutritional function of millet [J]. Journal of Northern Agriculture, 2022, 50(6): 113-118.
[10]	YUAN Yuwei, ZHANG Lei, FU Chongyi, SUN Pingping, WU Zhanmin, MA Qiang, LI Zhengnan. Research progress of three latent viruses in apple [J]. Journal of Northern Agriculture, 2021, 49(4): 83-97.
[11]	. Rainfed agriculture research progress at domestic and overseas [J]. Journal of Northern Agriculture, 2016, 44(1): 102-102.
[12]	. Progress of Biological Control in Protected Field Vegetable [J]. Journal of Northern Agriculture, 2014, (5): 95-95.
[13]	. The Current Situation of the Occurrence of Vegetable Root Knot Nematode and its Integrated Control Technique [J]. Journal of Northern Agriculture, 2012, (2): 70-70.
[14]	. The Research Progress of Environmental Impact Assessment of General Land Utilization Planning [J]. Journal of Northern Agriculture, 2010, (1): 36-36.