畜牧与饲料科学 ›› 2011, Vol. 32 ›› Issue (11): 23-23.doi: 10.12160/j.issn.1672-5190.2011.11.011

• 动物营养与饲料科学 • 上一篇    下一篇

中药添加剂对海南文昌鸡生长性能的影响及其安全性评价

姚茂忠[1] 陈湛娟[2] 马建升[3]   

  1. [1]海南医学院海南省药物安全性评价研究中心,海南海口571101 [2]海南师范大学化学与化工学院,海南海口570216 [3]广州龙沙有限公司,广东广州510288
  • 出版日期:2011-11-20 发布日期:2011-11-20
  • 通讯作者: 姚茂忠
  • 作者简介:姚茂忠(1981-),男,助理研究员,硕士,主要研究方向为动物营养与饲料安全。 通讯作者:马建升(1978-),男,工程师,硕士,主要研究方向为动物营养与免疫。

Effects of Traditional Chinese Medicine Additive on the Growth Performance of Hainan Wenchang Chicken and Its Safety Evaluation

YAO Mao-zhong, CHEN Zhan-juan, MA Jian-sheng (1.Research Center for Drug Safety Evaluation of Hainan Province,Hainan Medical College, Haikou 571101, China;2. College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 570216,China ;3. Guangzhou Lonza Co., Ltd., Guangzhou 510288, China)   

  • Online:2011-11-20 Published:2011-11-20

摘要: [目的]研究中药添加剂对海南文昌鸡生长性能的影响,并对其使用安全性进行评价。[方法]将180只雌性文昌鸡随机分为5组,每组3个重复,每重复12只。第1组为空白对照组,饲喂基础日粮;第2组为抗生素对照组.在基础日粮中添加600mg/kg的金霉素;第3,4、5组分别在基础日粮中添加0.1%、0.2%和013%的中药添加荆。生长试验共进行6周,每周称重。采用急性毒性试验、蓄积毒性试验对其安全性进行评价。[结果]0.2%中药添加剂能显著提高鸡的末体重(P〈0.05),中药添加剂的LDso〉10g/(kg·bw),蓄积系数K〉5。[结论]该中药添加剂为一种安全、有效的饲料添加剂。

Abstract: [Objective] The aim was to study effects of traditional Chinese medicine additive(TCMA)on the growth performance of Hainan Wenchang chicken and to evaluate its safety to mouse. [Method] 180 female Wenchang chicken were randomly assigned to 5 groups with 3 replications each,each replication contain 12 chickens. Diets containing 0 and 600 mg/kg aureomycin as well as 0. 1%, 0.2% and 0.3% TCMA were fed to group 1 ,group 2,goup 3 ,group 4 and group 5 ,respectively. The test for growth lasted 6 weeks,among them body weight was measured per 7 days. Acute toxicity test and accumulation toxicity test were used to evaluate the safety of TCMA. [Result] Ultimate body weight in 0.2% TCMA was improved significantly (P〈0.05). The median lethal dose (LD50)for mouse was more than 10 g/(kg-bw), and the accumulation coefficient K was more than 5. [Conclusion] TCMA is a safe feed additive with high performance.

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