Abstract: The entrepreneurship education was integrated into the professional education in facility agriculture science and engineering speciality of Weifang University. Relying on the local agricultural resources and entrepreneurial environment,the entrepreneurship guiding system was formed with school＇s entrepreneurship instruction as the basis and professional entrepreneurship culture as the guide. Through the construction and practice of the culture system, the employment concept of students was changed, the entrepreneurship consciousness was enhanced, entrepreneurial skills were improved, entrepreneurial spirit was cultivated. This laid a solid foundation for students＇ self-entrepreneurship after graduation.