畜牧与饲料科学 ›› 2019, Vol. 40 ›› Issue (4): 18-20.doi: 10.12160/j.issn.1672-5190.2019.04.005

• 著者文摘 • 上一篇    下一篇

铜对奶牛免疫能力的影响

王晓雅[1];贾大庆[1];韩杨[1];王建发[1];武瑞[1]   

  1. [1]黑龙江八一农垦大学动物科技学院,黑龙江大庆163319
  • 收稿日期:2019-03-05 出版日期:2019-04-30 发布日期:2019-08-19
  • 通讯作者: 王晓雅-黑龙江八一农垦大学动物科技学院,黑龙江大庆163319
  • 作者简介:王晓雅(1994—),女,硕士研究生,主要研究方向为兽医临床诊断与新兽药开发;通讯作者:武瑞(1967-),男,教授,博士,博士生导师,主要研究方向为兽医临床诊断与新兽药开发。
  • 基金资助:
    国家“十三五”重点研发计划“畜禽营养代谢与中毒性疾病防控技术研究”子任务“牛羊主要微量元素缺乏病早期诊断与监测技术的研究”(2016YFD0501203)。

Effect of Copper on Immune Ability of Dairy Cows

WANG Xiao-ya[1];JIA Da-qing[1];HAN Yang[1];WANG Jian-fa[1];WU Rui[1]   

  1. [1]College of Animal Science and Veterinary Medicine,Heilongjiang Bayi Agricultural University,Daqing 163319,China
  • Received:2019-03-05 Online:2019-04-30 Published:2019-08-19

摘要: [目的]检测实验奶牛血清中的微量元素铜的水平及相关指标的变化规律。[方法]实验所用实验动物均选自黑龙江地区某奶牛场,常规水平饲养管理,TMR全混合日粮自由采食。根据DHI数据随机选择体重、胎次(2~3次)、泌乳期(0~10d)、体况和饲养管理高度相似的泌乳奶牛50头。[结果]实验奶牛血清铜水平与IL-2的相关性为R=0.355,显著性为P=0.011。实验奶牛血清铜水平与IL-2呈显著正相关,泌乳奶牛血清中的IL-2会随着铜水平的升高而有所升高。实验奶牛血清铜水平与IL-1的相关性为R=0.215,显著性为Ρ=0.133,P>0.05。实验奶牛血清铜水平与IL-1不相关。实验奶牛血清铜水平与TNF-α的相关性为R=0.185,显著性为P=0.198,P>0.05。[结论]实验奶牛血清铜水平与TNF-α不相关。

关键词: 奶牛, 铜, 免疫能力, 免疫因子

Abstract: [Objective]To detect the serum level of trace element of copper in experimental dairy cows and to characterize the variation rule of related indexes.[Method]The experimental dairy cows used in this study were selected from a dairy farm in Heilongjiang Province,and were reared under free-choice feeding system with TMR diets.According to the DHI data,50 lactating cows with similar body weight,parity (2-3 times),lactation period (0-10 days),body condition and feeding management were randomly selected.[Result]The correlation between serum copper level and IL-2 content in the experimental dairy cows was R=0.355,P=0.011.There was a significantly positive correlation between serum copper level and IL-2 content in the experimental dairy cows.The serum content of IL-2 in the lactating dairy cows was increased with the elevation of serum copper level.The correlation between serum copper level and IL-1 content in the experimental dairy cows was R=0.215,and the significance was P=0.133,P>0.05.There was no correlation between serum copper level and IL-1 content in the experimental dairy cows.The correlation between serum copper level and TNF- alpha content in the experimental dairy cows was R=0.185,with a significant difference of P=0.198,P>0.05.[Conclusion]There was no correlation between serum copper level and TNF-alpha content in experimental dairy cows.

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