代谢组学技术在筛选奶牛脂肪肝生物标志物中的应用研究进展

doi:10.12160/j.issn.1672-5190.2023.01.006

摘要/Abstract

摘要：

脂肪肝是奶牛养殖过程中一种高发的营养代谢性紊乱病，会降低奶牛产奶量和平均使用寿命，影响后续生产性能的发挥，给奶牛养殖业造成巨大经济损失。组学技术的应用已经成为奶牛疾病研究的重要手段，可为预防和治疗奶牛脂肪肝提供理论基础和技术支撑。综述了代谢组学技术在筛选奶牛脂肪肝生物标志物中的应用研究进展，以期为生产实践中快速诊断和治疗奶牛脂肪肝提供参考。

关键词: 奶牛, 脂肪肝, 代谢组学, 生物标志物

Abstract:

Fatty liver is a metabolic disorder with high incidence in the perinatal period of dairy cows. This disease results in reductions in milk yield and average productive lifespan of dairy cows, seriously affects their subsequent production performance, and brings huge economic losses to the dairy farming industry. The application of metabonomics has become a hot technology in the study of dairy cow diseases, and can provide theoretical basis and technical support for the prevention and therapy of fatty liver in dairy cows. The research progress in application of metabonomics in screening biomarkers of fatty liver in dairy cows is reviewed, in hoping to give new insights into the rapid diagnosis and treatment of fatty liver in dairy cow production.

Key words: dairy cows, fatty liver, metabonomics, biomarkers

中图分类号:

S858.236.5

马贵, 安彦昊, 马莉花, 沙萍, 马燕芬. 代谢组学技术在筛选奶牛脂肪肝生物标志物中的应用研究进展[J]. 畜牧与饲料科学, 2023, 44(1): 38-43.

MA Gui, AN Yan-hao, MA Li-hua, SHA Ping, MA Yan-fen. Application of Metabonomics in Screening Biomarkers of Fatty Liver in Dairy Cows[J]. Animal Husbandry and Feed Science, 2023, 44(1): 38-43.

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