基于鸽胸肌转录组挖掘其卓越飞行性能的分子标记

doi:10.12160/j.issn.1672-5190.2020.04.005

畜牧与饲料科学 ›› 2020, Vol. 41 ›› Issue (4): 28-31.doi: 10.12160/j.issn.1672-5190.2020.04.005

基于鸽胸肌转录组挖掘其卓越飞行性能的分子标记

刘娜娜^1,2, 白雪^1,2, 孙燕勇^1,2, 特日格勒^1,2, 付绍印^2,3, 段仕^1,2, 刘永斌³, 张文广^1,2

1.内蒙古农业大学动物科学学院,内蒙古呼和浩特 010018;
2.动物遗传育种与繁殖内蒙古自治区重点实验室,内蒙古呼和浩特 010018;
3.内蒙古自治区农牧业科学院,内蒙古呼和浩特 010031

收稿日期:2020-04-30 出版日期:2020-07-30 发布日期:2020-08-19
通讯作者: 张文广（1973—）,男,教授,博士,博士生导师,主要研究方向为数量基因组学与性状遗传机理。
作者简介:刘娜娜（1994—）,女,硕士研究生,主要研究方向为数量基因组学与性状遗传机理。
基金资助:
2015年度内蒙古自治区草原英才团队项目

Analysis of Molecular Markers Genetically Associated with the Excellent Flight Performance of Pigeon Based on Pectoral Muscles Transcriptome

LIU Na-na^1,2, BAI Xue^1,2, SUN Yan-yong^1,2, Terigele^1,2, FU Shao-yin^2,3, DUAN Shi^1,2, LIU Yong-bin³, ZHANG Wen-guang^1,2

1. College of Animal Science,Inner Mongolia Agricultural University,Hohhot 010018,China;
2. Inner Mongolia Key Laboratory of Animal Genetics,Breeding and Reproduction,Hohhot 010018,China;
3. Inner Mongolia Academy of Agricultural and Animal Husbandry Sciences,Hohhot 010031,China

Received:2020-04-30 Online:2020-07-30 Published:2020-08-19

摘要/Abstract

摘要： 目的对赛鸽和观赏鸽胸肌组织的转录组进行比较分析,探讨鸽胸肌中与飞行性能相关的关键基因。方法通过差异分析获取赛鸽和观赏鸽胸肌中显著上调和下调的差异基因并进行富集分析。结果数据经质量控制共获得18.3 G的有效数据,筛选出477个差异表达基因,包含194个上调基因和130个下调基因。KEGG pathway显著性富集分析共筛选出3个与鸽飞行性能相关的候选基因,分别为MUSTN1、PDK4和MSTN。结论通过比较赛鸽和观赏鸽胸肌转录组数据,筛选与鸽飞行性能相关的关键基因,丰富了鸽的基因组信息,为进一步揭示鸽胸肌分子机理奠定了基础。

关键词: 赛鸽, 观赏鸽, 胸肌, 飞行性能

Abstract: [Objective] To compare and analyze the transcriptome of pectoral muscle tissues between racing pigeons and ornamental pigeons, and to explore the key genes related to flight performance in pigeon pectoral muscles. [Method] Through differential analysis, the differentially expressed genes that were significantly up-and down-regulated in pectoral muscles between racing pigeons and ornamental pigeons were obtained and enriched. [Result] A total of 18.3 G effective data were obtained by using data quality control. A total of 477 differentially expressed genes, including 194 up-regulated genes and 130 down-regulated genes were screened out. Three candidate genes related to pigeon flight performance were screened out by using KEGG pathway significance enrichment analysis : MUSTN1, PDK4 and MSTN. [Conclusion] By comparing the transcriptome data of the pectoral muscles between racing pigeons and ornamental pigeons, the key genes associated with flight performance of pigeon were obtained. The information provided by this study enriched the genomic information of pigeons and laid the foundation for further elaborating the molecular mechanism of pigeon pectoral muscles.

Key words: racing pigeon, ornamental pigeon, pectoral muscles, flight performance

中图分类号:

S836.2

刘娜娜, 白雪, 孙燕勇, 特日格勒, 付绍印, 段仕, 刘永斌, 张文广. 基于鸽胸肌转录组挖掘其卓越飞行性能的分子标记[J]. 畜牧与饲料科学, 2020, 41(4): 28-31.

LIU Na-na, BAI Xue, SUN Yan-yong, Terigele, FU Shao-yin, DUAN Shi, LIU Yong-bin, ZHANG Wen-guang. Analysis of Molecular Markers Genetically Associated with the Excellent Flight Performance of Pigeon Based on Pectoral Muscles Transcriptome[J]. Animal Husbandry and Feed Science, 2020, 41(4): 28-31.

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基于鸽胸肌转录组挖掘其卓越飞行性能的分子标记

Analysis of Molecular Markers Genetically Associated with the Excellent Flight Performance of Pigeon Based on Pectoral Muscles Transcriptome

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