改善早期断奶仔猪肠道健康和功能的营养策略研究进展

doi:10.12160/j.issn.1672-5190.2022.05.007

畜牧与饲料科学 ›› 2022, Vol. 43 ›› Issue (5): 39-47.doi: 10.12160/j.issn.1672-5190.2022.05.007

改善早期断奶仔猪肠道健康和功能的营养策略研究进展

张雪莉¹,刘晓丹¹,靳二辉^1,^2,³,杜民^1,²,张峰^1,²

1.安徽科技学院动物科学学院，安徽滁州 233100
2.动物营养调控与健康安徽省重点实验室，安徽滁州 233100
3.安徽安丰堂动物药业有限公司，安徽合肥 230000

收稿日期:2022-06-04 出版日期:2022-09-30 发布日期:2022-09-21
通讯作者: 张峰（1986—），男，讲师，博士，主要从事单胃动物肠道微生态与健康研究工作。
作者简介:张雪莉（2000—），女，所学专业为动物科学。
基金资助:
国家自然科学基金面上项目(32172816);安徽省自然科学基金项目(2108085MC117);安徽省自然科学基金项目(2208085MC77);安徽省高校自然科学研究重点项目(KJ2021A0868);安徽省现代农业产业技术体系建设专项资金资助(AHCYJSTX-05-16);动物营养调控与健康安徽省重点实验室开放课题项目(APKLANRH202001);安徽科技学院人才引进项目(DKYJ202101);大学生创新创业训练计划项目(S202110879182);大学生创新创业训练计划项目(S202110879179)

Advances in Nutritional Strategies for Improvement of Intestinal Health and Function in Early Weaned Piglets

ZHANG Xue-li¹,LIU Xiao-dan¹,JIN Er-hui^1,^2,³,DU Min^1,²,ZHANG Feng^1,²

1. College of Animal Science，Anhui Science and Technology University，Chuzhou 233100，China
2. Anhui Province Key Laboratory of Animal Nutrition Regulation and Health，Chuzhou 233100，China
3. Anhui Anfengtang Animal Medicine Industry Co.，Ltd.，Hefei 230000，China

Received:2022-06-04 Online:2022-09-30 Published:2022-09-21

摘要/Abstract

摘要：

商业化生产中仔猪早期断奶（3~4周龄）恰是肠道功能发育的关键时期，断奶应激带来的持续性肠道屏障功能损伤是断奶仔猪细菌性和病毒性肠炎及断奶后腹泻的主要诱因。饲料端“禁抗”背景下，运用营养策略改善早期断奶仔猪肠道功能的研究是研究者关注的焦点问题。从早期断奶对仔猪肠道屏障功能的影响及多种营养策略对断奶仔猪肠道功能改善的作用，综述了早期断奶致仔猪肠道屏障功能损伤的机理及氨基酸、抗菌肽、益生菌、膳食纤维、低聚糖、有机酸、微量营养素和脂质营养等营养策略改善仔猪肠道功能的作用机制，为通过营养策略改善断奶仔猪肠道功能相关研究提供参考。

关键词: 仔猪, 早期断奶, 肠道屏障功能, 肠道健康, 营养策略

Abstract:

In commercial swine production, the early weaning stage of piglets （3-4 weeks of age） is the key period of intestinal function development. Weaning stress is primarily responsible for the continuous intestinal barrier function deterioration that results in bacterial and viral enteritis, as well as post-weaning diarrhea in weaned piglets. Under the background of ′antibiotic-free′ in the feed end, researchers are focusing on adopting nutritional approaches to enhance the intestinal function of early weaned pigs. In this paper, the underlying mechanisms of intestinal barrier function damage caused by early weaning and those of improving intestinal function of piglets by nutritional strategies such as amino acids, antimicrobial peptides, probiotics, dietary fiber, oligosaccharides, organic acids, micro-nutrients, and lipid nutrition were reviewed in relation to the affects of early weaning on the intestinal barrier function of piglets and the impacts of various nutritional strategies on the improvement of intestinal barrier function of weaned piglets, in hoping to provide references for the research on improving the intestinal function of weaned piglets through nutritional strategy.

Key words: piglet, early weaning, intestinal barrier function, intestinal health, nutritional strategies

中图分类号:

S828.45

张雪莉, 刘晓丹, 靳二辉, 杜民, 张峰. 改善早期断奶仔猪肠道健康和功能的营养策略研究进展[J]. 畜牧与饲料科学, 2022, 43(5): 39-47.

ZHANG Xue-li, LIU Xiao-dan, JIN Er-hui, DU Min, ZHANG Feng. Advances in Nutritional Strategies for Improvement of Intestinal Health and Function in Early Weaned Piglets[J]. Animal Husbandry and Feed Science, 2022, 43(5): 39-47.

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改善早期断奶仔猪肠道健康和功能的营养策略研究进展

Advances in Nutritional Strategies for Improvement of Intestinal Health and Function in Early Weaned Piglets

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