植物miR159靶向MYB基因家族的调控作用及其跨界调控哺乳动物生理功能的研究进展

doi:10.12160/j.issn.1672-5190.2022.05.008

摘要/Abstract

摘要：

植物miR159靶向MYB基因家族在植物的生长发育、新陈代谢、逆境响应及病原防御等多种生理过程中发挥关键作用。植物miR159可以跨界调控哺乳动物的生理功能，如抑制肿瘤生长、改善能量代谢、抗氧化应激、调节机体免疫功能等。阐述了miR159通过调控MYB基因家族参与多种植物营养生长、逆境胁迫、开花和果实发育过程，以及外源性植物miR159跨界调控哺乳动物生理功能和对乳腺癌的调控作用，以期为后续深入研究植物miR159的调控网络以及跨物种调控机制提供参考。

关键词: miR159, MYB家族, 跨界调控, 生理功能

Abstract:

Plant miR159 has been found to play a key role in a variety of physiological processes such as growth and development, metabolism, response to stress, and pathogen defense in plant by targeting MYB gene family. It has also been proved to have a cross-kingdom regulative role in mammalian physiological functions, such as inhibition of tumor growth, improvement of energy metabolism, anti-oxidative stress and regulation of immunity. This paper described the involvement of miR159 in regulation of nutritional growth, response to stress, flowering and fruit development in a variety of plants, and reviewed the cross-kingdom regulative role of exogenous plant miR159 in mammalian physiological functions and breast cancer, in hoping to provide references for the subsequent study on the regulative network and cross-kingdom regulative mechanism of plant miR159.

Key words: miR159, MYB family, cross-kingdom regulation, physiological functions

中图分类号:

S814.2

段红娟, 孟桂智, 刘宝宝, 贾晶莹, 马燕芬, 马云, 蔡小艳. 植物miR159靶向MYB基因家族的调控作用及其跨界调控哺乳动物生理功能的研究进展[J]. 畜牧与饲料科学, 2022, 43(5): 48-54.

DUAN Hong-juan, MENG Gui-zhi, LIU Bao-bao, JIA Jing-ying, MA Yan-fen, MA Yun, CAI Xiao-yan. Advances in Regulative Role of Plant miR159 Targeting MYB Gene Family and Its Cross-kingdom Regulation in Mammalian Physiological Functions[J]. Animal Husbandry and Feed Science, 2022, 43(5): 48-54.

图/表 1

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