Abstract: Pseudomonas aeruginosa is a conditional pathogenic bacteria existing in environment and normal livestock and poultry body. In recent years, with the deepening of animal disease research, more and more Pseudomonas aeruginosa infections have been reported. In order to lay the foundation for the control of Pseudomonas aeruginosa infection, research advances on Pseudomonas aeruginosa were reviewed from some aspects of etiology, epidemiology, pathogenesis and clinical in this paper.