Abstract: A clinical survey on 956 sick canines of a pat hospital in Nanning City of Guangxi was carried out in 2012, and the survey contents mainly included morbidity, onset season and age of canine parvovirus, relationship between purity of canine variety and morbidity, effects of immunity on canine parvovirus, etc. The results showed that the disease incidence of canine parvovirus was high in Nanning, reaching 14.3%; it mainly appeared in spring, late autumn and winter; canines under each age could suffer the disease, but morbidity and mortality of young canines were higher; the best way to prevent the disease is immunity.