Abstract: The extraction rate of Euphorbiafischeriana with different extracting solutions, different times of extracting solutions and different extraction methods were studied. And the components of the extracts by using different extracting solutions and extraction methods were analyzed. The results showed that the extraction rate of using methanol as extracting solution, soaking at 6 times of room temperature, Soxhlet extraction and soaking at room temperature was the highest. And the extraction rate of using 95% ethanol as extracting solution by the same extraction method was the next. The extraction rate of using 95% ethanol, petroleum ether and ethyl acetate as extracting solution, soaking at 6 times of room temperature, Soxhlet extraction and soaking at room temperature was higher than that of other methods. The extraction rate of using methanol as extracting solution by the same method was the highest and its extracts had most components, followed by ethanol. Therefore methanol and ethanol were suitable extracting solutions for crude extraction of E. fischeriana. The best extraction method was soaking at 6 times of room temperature, Soxhlet extraction and soaking at room temperature.