Abstract: [Objective] The research aimed to study the effects of sheep placental transfer factor injection on the cellular immunity of animals. [Method] Taking rabbits and Kunxi mice as test objects, the effects of sheep placental transfer factor injection on the quantity and activity of T lymphocyte in rabbit and its activation on the lymphocyte of mice were detected by using E rosette test and lymphocyte transformation test. [Result] Sheep placental transfer factor injection had the functions of significantly increasing the quantity and activity of lymphocyte, which could obviously enhance the transformation rate of lymphocytes. [Conclusion] Sheep placental transfer factor injection could improve and enhance the specific cellular immunity of test animals.