Abstract: The present study reported the case of a 10-year-old male Chow Chow weighing 15 kg with suspected arthrolithiasis that presented with listlessness, inappetence, increased water intake, dry stool, increased urination, lying without movement, and ache of lower limb. The presence of swelling of intra-articular soft tissue of the extremities was observed by X-ray analysis; the blood routine examination demonstrated the elevated leukocyte count and the decreased blood platelet; increased serum level of AST and ALB as well as significantly increased serum level of uric acid was found by blood biochemical examination. A definite diagnosis of arthrolithiasis was made based on the above diagnostic results. The combined therapy of Chinese and Western medicine achieved a satisfactory effect.