Abstract: Coccidiosis is a serious hazard to livestock and poultry breeding industry. Animals have high mortality after coccidian infection, and the clinically tolerant animals always have weight loss and growth retardation. Chinese herbal medicine has the effects of improving the disease resistance of livestock and poultry, relieving clinical symptoms of coccidiosis and promoting the growth of livestock and poultry, which was considered as a new type of coccidiostat with low toxicity, high efficiency, and good safety and environment-friendless. By referring the literatures regarding prevention and treatment of coccidiosis in livestock and poultry with Chinese herbal medicine, the advances in research and development of anticoccidial preparation and the corresponding application prospects were introduced, in hoping to provide references for the scientific prevention and treatment of coccidiosis.