Abstract: In order to evaluate the effect of dietary supplementation of compound enzyme on growth performance of lamb, a total of 60 2.5-month-old weaned lambs were selected and randomly divided into three groups according to their weight, including a control group and two experimental groups. All of the groups were reared under the same feeding condition and fed with the same basal diet. The experimental groupⅠand Ⅱ received addition of 0.1% and 0.2% compound enzyme in basal diet, respectively. The results showed that compared to the control group, the average daily gain of the experimental groupⅠand Ⅱ was elevated by 10.90%(P <0.05) and 13.02%(P <0.05), respectively;the experimental group Ⅱ had significantly lower feed -gain ratio compared to the control group and experimental groupⅠ(P<0.05);there were no significant differences in contents of serum urea nitrogen and triglyceride between control group and the two experimental groups (P>0.05);the significantly higher contents of blood sugar, total protein and total cholesterol were observed in the two experimental groups compared to the control group (P< 0.05). Collectively, the experimental groupⅡ(dietary supplementation of 0.2% compound enzyme) showed the best feeding effect in lambs.