血小板衍生因子A的生理功能研究进展

doi:10.12160/j.issn.1672-5190.2021.04.010

Abstract

Abstract: Platelet-derived growth factor A （PDGFA） is a kind of polypeptides in the PDGF family, which has the functions of promoting cell growth, stimulating the interactions between cells and intercellular substances, and influencing wool follicle growth. This paper reviews the protein structure of PDGFA, the main expression pathways of Wnt, SHH and BMP of PDGFA, and the roles of PDGFA in skin, lung and wool growth. Furthermore, the important roles of PDGFA in wool follicle growth and cycle maintenance are elaborated, in hoping to provide a basis for further researches on mechanisms of wool growth.

Key words: PDGFA gene, structure and expression, expression pathway, physiological functions, wool follicle growth

CLC Number:

Q592.1

WU Zi-xian, LI Yun-hua, ZHANG Bin, ZHANG Jun, ZHAO Yan-hong, LIU Jia-sen. Research Advances on Physiological Functions of Platelet-derived Growth Factor A[J]. Animal Husbandry and Feed Science, 2021, 42(4): 49-53.

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Research Advances on Physiological Functions of Platelet-derived Growth Factor A

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