Wnt10b基因的生理功能及其在绒毛周期性生长中的作用研究进展

doi:10.12160/j.issn.1672-5190.2020.03.005

Abstract

Abstract: The cashmere growth of cashmere goat has the characteristic of periodicity and is affected by many factors. Wnt10b gene, as one of the important members of Wnt family, plays an important role in the formation of fat and bone, occurrence of some diseases （such as tumor）, generation of hair follicle, and the growth and active state maintenance of hair plate in animal. In this paper, the origin, structure, physiological function, regulatory mechanism of Wnt10b and its influence on the growth cycle of hair follicle are reviewed, in hoping to provide reference for understanding the mechanism of Wnt10b in promoting the periodic growth of cashmere.

Key words: cashmere goat, Wnt10b gene, hair follicle, periodic growth

CLC Number:

Q753

MU Qing, WANG Rui-xue, WANG Rong, ZHOU Jian, LIU Jun-yang, LIU Jia-sen, ZHAO Yan-hong. Research Advances on Physiological Function of Wnt10b Gene and Its Role in Periodic Growth of Cashmere[J]. Animal Husbandry and Feed Science, 2020, 41(3): 22-27.

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References 38

[1]	HARDIMAN G,ALBRIGHT S,TSUNODA J,et al.The mouse Wnt-10B gene isolated from helper T cells is widely expressed and a possible oncogene in BR6 mouse mammary tumorigenesis[J].Gene,1996,172(2):199-205.
[2]	LEE F S,LANE T F,KUO A,et al.Insertional mutagenesis identifies a member of the Wnt gene family as a candidate oncogene in the mammary epithelium of int-2/Fgf-3 transgenic mice[J].Proceedings of the National Academy of Sciences of the United States of America,1995,92(6):2268-2272.
[3]	KRAUSS S,KORZH V,FJOSE A,et al.Expression of four zebrafish wnt-related genes during embryogenesis[J].Development,1992,116(1):249-259.
[4]	刘维,张文广,王志新,等.Wnt10b在绒山羊皮肤中的表达[J].黑龙江畜牧兽医,2011(1):1-3.
[5]	杨映娟,李惠侠,杨公社.猪Wnt10b基因cDNA的克隆及生物信息学分析[J].中国生物化学与分子生物学报,2008,24(7):679-683.
[6]	林森,林亚秋,朱江江,等.山羊Wnt10b基因生物学特征及组织细胞表达模式分析[J].基因组学与应用生物学,2017(10):4070-4078.
[7]	VISWESWARAN M, POHL S, ARFUSO F, et al.Multi-lineage differentiation of mesenchymal stem cells-To Wnt, or not Wnt[J].The International Journal of Biochemistry and Cell Biology,2015,68:139-147.
[8]	CHUNG S S, LEE J S, KIM M,et al.Regulation of Wnt/β-catenin signaling by CCAAT/enhancer binding protein β during adipogenesis[J].Obesity,2012,20(3):482-487.
[9]	MARTÍNEZ DEL PINO L, ARANA A, ALFONSO L,et al. Adiposity and adipogenic gene expression in four different muscles in beef cattle[J].PLoS One,2017,12(6):e0179604.
[10]	LONGO K A,WRIGHT W S,KANG S,et al.Wnt10b inhibits development of white and brown adipose tissues[J].Journal of Biological Chemistry,2004,279(34):35503-35509.
[11]	YIEW N K H,CHATTERJEE T K,TANG Y L,et al.A novel role for the Wnt inhibitor APCDD1 in adipocyte differentiation: Implications for diet-induced obesity[J].Journal of Biological Chemistry,2017,292(15):6312-6324.
[12]	COLLINS F L, RIOS-ARCE N D, MCCABE L R,et al. Cytokine and hormonal regulation of bone marrow immune cell Wnt10b expression[J].PLoS One,2017,12(8):e0181979.
[13]	WU M,WANG Y,SHAO J Z,et al.Cbfβ governs osteoblast-adipocyte lineage commitment through enhancing β-catenin signaling and suppressing adipogenesis gene expression[J].Proceedings of the National Academy of Sciences of the United States of America,2017,114(38):10119-10124.
[14]	JING H,SU X,GAO B,et al.Epigenetic inhibition of Wnt pathway suppresses osteogenic differentiation of BMSCs during osteoporosis[J].Cell Death and Disease,2018,9(2):176.
[15]	FITRI A R,PAVASANT P,CHAMNI S,et al.Asiaticoside induces osteogenic differentiation of human periodontal ligament cells through the Wnt pathway[J].Journal of Periodontology,2018,89(5):596-605.
[16]	LU C,SHYU J,WU C,et al.Association of anabolic effect of calcitriol with osteoclast-derived Wnt10b secretion[J].Nutrients,2018,10(9):1164.
[17]	WEND P, WEND K, KRUM S A,et al.The role of WNT10B in physiology and disease[J].Acta physiologica,2011,204(1):34-51.
[18]	CHEN Y,ZENG C,ZHAN Y,et al.Aberrant low expression of p85α in stromal fibroblasts promotes breast cancer cell metastasis through exosome-mediated paracrine Wnt10b[J].Oncogene,2017,36(33):4692-4705.
[19]	陈红漫. Wnt10a/Wnt10b及其Wnt/β-catenin通路在子宫内膜癌中的作用研究[D].天津:天津医科大学,2014.
[20]	LU H,JU D,YANG G,et al.Targeting cancer stem cell signature gene SMOC-2 overcomes chemoresistance and inhibits cell proliferation of endometrial carcinoma[J].EBioMedicine,2019,40:276-289.
[21]	YUZUGULLU H, BENHAJ K,OZTURK N,et al.Canonical Wnt signaling is antagonized by noncanonical Wnt5a in hepatocellular carcinoma cells[J].Molecular Cancer,2009,8(1):90.
[22]	浮凤洲,范晓丽,孙莉.Wnt10b在肝细胞肝癌中的表达[J].重庆医学,2014(28):3753-3756.
[23]	王林,许晓群,王郡甫.胃癌组织Wnt10b的表达及意义[J].济宁医学院学报,2014,37(1):30-32.
[24]	刘永明. Wnt10b及β-catenin在骨肉瘤组织中的表达及其临床意义[D].长沙:中南大学,2010.
[25]	PENG L,LIU Z,XIAO J,et al.MicroRNA-148a suppresses epithelial-mesenchymal transition and invasion of pancreatic cancer cells by targeting Wnt10b and inhibiting the Wnt/-catenin signaling pathway[J].Oncology Reports,2017,38(1):301-308.
[26]	林可焴,苏颖,何火聪,等.Wnt10b、β-catenin与鼻咽癌放射敏感性的关系[J].福建医药杂志,2016(6):81-85.
[27]	ULLAH A,GUL A,UMAIR M,et al.Homozygous sequence variants in the WNT10B gene underlie split hand/foot malformation[J].Genetics and Molecular Biology,2018,41(1):1-8.
[28]	DANIELS D L,EKLOF SPINK K,WEIS W I.β-catenin: molecular plasticity and drug design[J].Trends in Biochemical Science,2001,26(11):672-678.
[29]	张志丹,胡志奇,李科成,等.Wnt10b对体外培养的人毛乳头细胞诱导毛囊生成能力的影响[J].实用医学杂志,2013,29(5):688-691.
[30]	赵帅,岳耀敬,郭婷婷,等.Wnt10b、β-catenin、FGF18基因在甘肃高山细毛羊胎儿皮肤毛囊中的表达规律研究[J].甘肃农业大学学报,2015(5):6-14.
[31]	张坤,连小华,李玉红,等.Wnt10b在小鼠毛囊周期中的表达[J].第三军医大学学报,2009,31(10):891-894.
[32]	WU P,ZHANG Y,XING Y,et al.The balance of Bmp6 and Wnt10b regulates the telogen-anagen transition of hair follicles[J].Cell Communication and Signaling ,2019,17:16.
[33]	WU Z,SUN L,LIU G,et al.Hair follicle development and related gene and protein expression of skins in Rex rabbits during the first 8 weeks of life[J].Asian Australasian Journal of Animal Sciences,2019,32(4):477-484.
[34]	HARDELAND R.Melatonin, hormone of darkness and more: occurrence, control mechanisms, actions and bioactive metabolites[J].Cellular and Molecular Life Sciences,2008,65(13):2001-2018.
[35]	常子丽. 持续埋植褪黑素对绒山羊绒毛生长特性和相关基因影响的研究[D].呼和浩特:内蒙古农业大学,2010.
[36]	王岩. 基于RNA-seq分析褪黑素对内蒙古绒山羊毛囊发育相关基因表达的影响[D].呼和浩特:内蒙古农业大学,2017.
[37]	丽春,张文广,常子丽,等.Wnt10b参与外源褪黑激素促进绒山羊绒毛生长的研究[J].中国畜牧杂志,2012,48(7):5-8.
[38]	穆卿. 褪黑激素对内蒙古绒山羊毛囊生长周期及Wnt10b、β-catenin基因表达的影响[D].呼和浩特:内蒙古农业大学,2018.

Research Advances on Physiological Function of Wnt10b Gene and Its Role in Periodic Growth of Cashmere

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