畜牧与饲料科学 ›› 2014, Vol. 35 ›› Issue (9): 11-11.doi: 10.12160/j.issn.1672-5190.2014.09.006

• 基础科学 • 上一篇    下一篇

鼻敏颗粒剂水提工艺的正交优选

张农山[1] 张立[2] 王培民[1]   

  1. [1]江苏省中医院,江苏南京210029 [2]南京中医药大学,江苏南京210029
  • 出版日期:2014-09-20 发布日期:2014-09-20
  • 通讯作者: 张农山
  • 作者简介:张农山(1982-),男,研究实习员,硕士,主要从事中医药临床科研工作。
  • 基金资助:
    江苏省中医院院级课题资助(Y12044)

Orthogonal Optimization of Water-extracting Technology of Allergic Rhinitis Granule

ZHANG Nong-shan, ZHANG Li, WANG Pei-min (1.Jiangsu Province Hospital of Traditional Chinese Medicine, Nanjing 210029,China,2.Nanjing University of Chinese Medicine,Nanjing 210029, China)   

  • Online:2014-09-20 Published:2014-09-20

摘要: [目的]优选鼻敏颗粒剂的最佳水提工艺。[方法]采用正交实验设计,以干浸膏得率、芍药苷含量为指标进行评价,对鼻敏颗粒剂水提取工艺进行了L9(3^4)正交实验。[结果]最佳提取工艺条件是加水量为药材量的8倍煎煮3次,每次2.0 h。[结论]水提取方法具有简便、科学、合理、可行的特点,有利于降低实际生产成本,可在保证鼻敏颗粒剂临床疗效持续稳定的基础上进行工业生产。

Abstract: [Objective] The research aimed to optimize the optimum water-extracting technology of allergic rhinitis granule.[Method] Taking the yield of dry extract and paeoniflorin content as evaluation indices, the extraction technology of allergic rhinitis granule was studied by using L9(3^4)orthogonal experiment. [Result] The optimum extraction technology conditions were as follows:adding water with the amount 8 times as the amount of medicinal materials, decocting for 2.0 h for 3 times.[Conclusion] Water-extracting technology was simple,scientific, reasonable and feasible. The production cost could be reduced by using water-extracting technology. And the water-extracting technology could be applied in industrial production on the basis of ensuring the stable clinical curative effect of allergic rhinitis granule.

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