畜牧与饲料科学 ›› 2023, Vol. 44 ›› Issue (6): 123-128.doi: 10.12160/j.issn.1672-5190.2023.06.016

• 动物疾病防控 • 上一篇    

噬菌体在畜禽业中的应用研究进展

任仕航, 段慧慧, 杜向党, 商艳红   

  1. 河南农业大学动物医学院,河南 郑州 450002
  • 收稿日期:2023-07-27 出版日期:2023-11-30 发布日期:2024-01-11
  • 通讯作者: 商艳红(1977—),女,副教授,硕士生导师,主要从事细菌耐药性及耐药机制研究工作。
  • 作者简介:任仕航(1999—),女,硕士研究生,主要研究方向为细菌耐药性及噬菌体。
  • 基金资助:
    河南省高校科技创新团队项目(18IRTSTHN020); 河南省重点研发与推广专项(科技攻关)(立项编号:232102110094)

Research Progress in the Application of Bacteriophages in Livestock and Poultry Industry

REN Shihang, DUAN Huihui, DU Xiangdang, SHANG Yanhong   

  1. College of Veterinary Medicine,Henan Agricultural University,Zhengzhou 450002,China
  • Received:2023-07-27 Online:2023-11-30 Published:2024-01-11

摘要: 抗生素在畜牧行业的长期广泛使用导致了严重的药物残留和细菌耐药性等问题,严重威胁了动物乃至人类的健康。噬菌体是一种可以侵袭和裂解细菌的病毒,具有特异性强、存在广泛、研发成本低等优势。随着科技的不断发展,噬菌体在畜禽业中的研究不断深入,其被作为抗生素的替代策略逐渐被人们重视起来。从噬菌体的生物学特性出发,阐述噬菌体治疗畜禽细菌性感染的研究以及噬菌体在畜禽养殖、食品生物控制等方面的开发应用,以期为噬菌体在畜禽生产中的应用提供参考。

关键词: 噬菌体, 抗生素, 多重耐药, 噬菌体疗法, 畜禽生产

Abstract: The long-term and widespread use of antibiotics in the animal husbandry industry has led to serious problems such as drug residues and antibiotic resistance, which seriously threatens the health of animals and even humans. Bacteriophages are viruses that can invade and lyse bacteria, with the advantages of strong specificity, wide presence, and low research and development cost. With the continuous development of science and technology, the research of bacteriophages in the livestock and poultry industry has been deepened, and the use of bacteriophages is progressively gaining recognition as an alternative strategy to antibiotics. Starting from the biological characteristics of bacteriophages, this article elaborates on the research of bacteriophages therapy for bacterial infections in livestock and poultry as well as the development and application of bacteriophages in livestock and poultry breeding, food biological control, etc., in hoping to provide references for the application of bacteriophages in livestock and poultry production.

Key words: bacteriophages, antibiotics, multi-drug resistance, bacteriophages therapy, livestock and poultry production

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