GnRH类似物疫苗免疫去势效果的影响因素

doi:10.12160/j.issn.1672-5190.2019.11.015

畜牧与饲料科学 ›› 2019, Vol. 40 ›› Issue (11): 61-64.doi: 10.12160/j.issn.1672-5190.2019.11.015

GnRH类似物疫苗免疫去势效果的影响因素

邢雪静, 尹国安

黑龙江八一农垦大学,黑龙江大庆 163319

收稿日期:2019-09-09 出版日期:2019-11-30 发布日期:2019-12-19
通讯作者: 尹国安（1982—）,男,副教授,博士,硕士生导师,主要研究方向为动物福利与生产。
作者简介:邢雪静（1996—）,女,硕士研究生,主要研究方向为动物福利与生产。
基金资助:
黑龙江省普通本科高等学校青年创新人才培养计划（UNPYSCT-2017107）

Influencing Factors on Immune Castration Effect Using GnRH Analogue Vaccines

XING Xue-jing, YIN Guo-an

Heilongjiang Bayi Agricultural University,Daqing 163319,China

Received:2019-09-09 Online:2019-11-30 Published:2019-12-19

摘要/Abstract

摘要： 利用GnRH类似物疫苗主动免疫动物机体可达到与手术去势类似的效果,同时避免了手术去势对动物机体产生的影响。抗原、佐剂、免疫次数、免疫剂量以及免疫时间都会对其免疫效果产生影响。采用GnRH类似物疫苗免疫动物通常需要有力的佐剂以及多次加强免疫来克服个体反应的差异性。

关键词: 促性腺激素释放激素, 免疫去势, 并列二聚体, 偶联蛋白, 佐剂, 疫苗

Abstract: Active immunization with GnRH analogue vaccines can achieve similar effects with surgical castration in animals, avoiding the affects of surgical castration on animal health. Antigens, adjuvants, immunization times, immunization doses, and immunization time point of GnRH analogue vaccines all have effects on their immune response. Immunization with GnRH analogue vaccines in animals often requires potent adjuvants and multiple boosts to overcome differences in individual responses.

Key words: GnRH, immune castration, parallel dimer, coupling protein, adjuvant, vaccine

中图分类号:

S852.5

邢雪静, 尹国安. GnRH类似物疫苗免疫去势效果的影响因素[J]. 畜牧与饲料科学, 2019, 40(11): 61-64.

XING Xue-jing, YIN Guo-an. Influencing Factors on Immune Castration Effect Using GnRH Analogue Vaccines[J]. Animal Husbandry and Feed Science, 2019, 40(11): 61-64.

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GnRH类似物疫苗免疫去势效果的影响因素

Influencing Factors on Immune Castration Effect Using GnRH Analogue Vaccines

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