奶牛亚急性瘤胃酸中毒（SARA）的易感因素及其对瘤胃功能的影响

doi:10.12160/j.issn.1672-5190.2022.05.009

畜牧与饲料科学 ›› 2022, Vol. 43 ›› Issue (5): 55-60.doi: 10.12160/j.issn.1672-5190.2022.05.009

奶牛亚急性瘤胃酸中毒（SARA）的易感因素及其对瘤胃功能的影响

杨坤¹,胡红莲²,李大彪¹,李兰柱³,张剑霞¹,钱娜¹,于良义¹,白梦婷¹,郭琳¹,高民²

1.内蒙古农业大学动物科学学院，内蒙古呼和浩特 010018
2.内蒙古自治区农牧业科学院动物营养与饲料研究所，内蒙古呼和浩特 010031
3.东北农业大学，黑龙江哈尔滨 150030

收稿日期:2022-04-23 出版日期:2022-09-30 发布日期:2022-09-21
通讯作者: 高民（1963—），男，研究员，博士，主要从事反刍动物营养调控理论与技术研究工作。
作者简介:杨坤（1997—），男，硕士研究生，主要研究方向为反刍动物营养与饲料。
基金资助:
内蒙古自治区科技计划项目(2021GG0028);内蒙古农牧业创新基金项目(2021CXJJM02);财政部和农业农村部：国家现代农业产业技术体系(CARS-36)

Predisposing Factors for Subacute Ruminal Acidosis (SARA) and Its Affects on Ruminal Function in Dairy Cows

YANG Kun¹,HU Hong-lian²,LI Da-biao¹,LI Lan-zhu³,ZHANG Jian-xia¹,QIAN Na¹,YU Liang-yi¹,BAI Meng-ting¹,GUO Lin¹,GAO Min²

1. College of Animal Science，Inner Mongolia Agricultural University，Hohhot 010018，China
2. Institute of Animal Nutrition and Feed，Inner Mongolia Academy of Agricultural and Animal Husbandry Sciences，Hohhot 010031，China
3. Northeast Agricultural University，Harbin 150030，China

Received:2022-04-23 Online:2022-09-30 Published:2022-09-21

摘要/Abstract

摘要：

在奶牛养殖中，亚急性瘤胃酸中毒（subacute ruminal acidosis，SARA）是一种高发的营养代谢病。随着我国奶牛养殖集约化程度的提高，为提升奶牛生产性能饲喂大量高能谷物饲料极易诱发SARA，导致瘤胃液pH值降低，瘤胃菌群发生改变，瘤胃上皮黏膜层受损，进而影响瘤胃代谢功能。分析了奶牛不同生理阶段、择食行为以及个体差异等SARA的易感因素，探讨了SARA对奶牛瘤胃菌群变化、瘤胃上皮细胞基因表达、瘤胃屏障功能的影响，以期为阐明SARA造成瘤胃功能损伤的机制、降低奶牛发生SARA的风险提供参考。

关键词: 奶牛, 亚急性瘤胃酸中毒, 易感因素, 瘤胃功能

Abstract:

Subacute ruminal acidosis （SARA） is a nutritional metabolic disease with a high frequency in dairy farming. With the development of intensive dairy farming in China, feeding a large amount of high-energy grain feed to improve the production performance of dairy cows is prone to develop SARA, which lowers the ruminal fluid pH value, alters the ruminal bacterial flora, impairs the ruminal epithelial mucosa, and eventually affects the ruminal metabolic function. This paper analyzed the predisposing factors of SARA including various physiological stages, feed intake behaviors and individual differences of dairy cows, discussed the affects of SARA on the changes of ruminal bacterial flora, gene expression of ruminal epithelial cells and ruminal barrier function of dairy cows, in hoping to provide references for elucidating the mechanisms of ruminal function damage caused by SARA and reducing the risk of SARA in dairy cows.

Key words: dairy cows, subacute ruminal acidosis, predisposing factors, ruminal function

中图分类号:

杨坤, 胡红莲, 李大彪, 李兰柱, 张剑霞, 钱娜, 于良义, 白梦婷, 郭琳, 高民. 奶牛亚急性瘤胃酸中毒（SARA）的易感因素及其对瘤胃功能的影响[J]. 畜牧与饲料科学, 2022, 43(5): 55-60.

YANG Kun, HU Hong-lian, LI Da-biao, LI Lan-zhu, ZHANG Jian-xia, QIAN Na, YU Liang-yi, BAI Meng-ting, GUO Lin, GAO Min. Predisposing Factors for Subacute Ruminal Acidosis (SARA) and Its Affects on Ruminal Function in Dairy Cows[J]. Animal Husbandry and Feed Science, 2022, 43(5): 55-60.

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奶牛亚急性瘤胃酸中毒（SARA）的易感因素及其对瘤胃功能的影响

Predisposing Factors for Subacute Ruminal Acidosis (SARA) and Its Affects on Ruminal Function in Dairy Cows

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