Abstract: The aim of the present study was to understand the status of veterinary drug residues in milk and dairy products in Hohhot. Field investigation and questionnaire survey were conducted to investigate the sales of milk and dairy products from 65 supermarkets and 60 milk products specialty stores; the consumption of milk and dairy products of 139 residents in Hohhot was investigated; the status of veterinary drug use in clinic was investigated by the information collected from 35 veterinarians and 10 experts. A retrospective survey was conducted to investigate the detection results of veterinary drug residue of 370 milk samples from Hohhot by authoritative testing institution using LC-MS-MS, ELISA and other methods from 2014 to 2015. The veterinary drug residues of 74 dairy product samples in Hohhot were detected by HPLC. The results showed that 96.41% of the respondent in Hohhot consumed milk and dairy products, 56.11% of consumers concerned the problem of veterinary drug residue in dairy products; 94.46% of the milk sold in market of Hohhot was provided by the local dairy farm, and the other 5.54% was provided from other areas; 94.44% of the investigated dairy farms had full-time veterinarians; the veterinarians in 20% of the surveyed dairy farms had overused veterinary drug; 85.71% of the surveyed dairy farms had medication records; 94.29 % of the surveyed dairy farms strictly enforced the veterinary drug withdrawal period; all of the surveyed dairy farms tested the antibiotics in raw milk; currently the most commonly used antimicrobial drugs are penicillin, ampicillin, amoxicillin and cephalosporins followed by gentamicin and metronidazole. Laboratory tests results showed that the residues in milk produced in Hohhot from 2014 to 2015 were all negative and no residue was detected in the samples of commercial dairy products. The production and distribution of milk and dairy products in municipal districts of Hohhot are in line with the requirements of the maximum residue limits of veterinary drugs in animal foods.