Abstract: Mycotoxin is a toxic secondary metabolites produced by mold with a broad range of chemical structure. The poisoning of mycotoxin in animals results in injury of liver, kidney and other organs and causes digestive and metabolic disorders, which increases the susceptibility of animals to diseases and increases mortality. The deposit of mycotoxin in body of food animals may transfer to human by food chain and poses great threat to human health. Therefore, the research of feed mycotoxins adsorbent is significant for the healthy development of breeding industry and human food safety. Currently, the commonly used feed detoxication methods include physical detoxication method, chemical detoxication method, biological detoxication method and compound adsorbent detoxication method. The mycotoxins adsorbents are most commonly used to absorb the mycotoxins in mildewed feed and the mainly used adsorbents are activated carbon, aluminosilicates （montmorillonite, zeolite powder, bentonite, etc.）, and organic compounds （yeast cell wall polysaccharides, etc.）. The mycotoxins adsorbents are widely used in poultry, swine, and dairy cow feed. Although the application of compound mycotoxins adsorbents is an effective way to solving the problem of feed mycotoxins contamination, the issues such as adsorption of nutrients in feed by mycotoxins adsorbents and the generally accepted evaluation standard for absorbing effect of mycotoxins adsorbents are worthy to be discussed.