Abstract: In order to assess the partial replacement of conventional feedstuff by dietary supplementation of a commercially available yeast culture Beitaide on lactation performance of sows,a total of 24 healthy pregnant sows with the same breed,weight and parity were selected 7 days before delivery and were divided into 3 groups.Group A was the control group without yeast culture,group B was the experimental group with Beitaide yeast culture replacing 5%bran of group A,and group C was the experimental group with Beitaide yeast culture replacing 2%soybean meal and 3%corn of group A.The results showed that the average weight of piglets in group B at 10 and 18 days of age was significantly higher than that in the other two groups.The average daily gain of piglets from 0-to 18-day-old in group B,group A and group C was 230.55 g,185.56 g and 178.89 g,respectively.The average daily gain of group B was significantly higher than that of group A and C by 24.25%and 28.87%,respectively.Although there was no significant difference in survival rate among group A,group B and group C,group B performed better.The group B had significantly better performance in milk yield compared to the other two groups.In conclusion,the rational dietary supplementation of Beitaide yeast culture in lactation period improves the growth performance of piglets and the lactation performance of sows to a certain extent.